the community site for and by developmental biologists

Hello from Alex

Posted by on December 17th, 2018

Hello, I’m Alex and I’m very happy to introduce myself as a new Reviews Editor for Development. I will be working together with invited authors to produce interesting and relevant reviews, opinion pieces and posters for our community. It’s really exciting to be at the forefront of research! Before joining the Company of Biologists, I[…]

This month in preLights – November

Posted by on December 14th, 2018

Welcome to our monthly summary of developmental biology (and related) preLights     In our last post of the year, we again have plenty of exciting research to feature, and would like to thank all the preLighters for their incredible work selecting and highlighting interesting preprints in a broad range of topics for the community.[…]

Visualizing the heterogeneity of single cell data from time-lapse imaging

Posted by on December 12th, 2018

When we examined the kinetics of Rho GTPase activity in endothelial cells in response to receptor stimulation (Reinhard, 2017), we noticed considerable cell-to-cell heterogeneity. In the original work we published graphs with the average response, reflecting the response of the whole cell population. However, these graphs fail to show the cellular heterogeneity. What is the[…]

A day in the life of a Kabuto-mushi (rhinoceros beetle) lab

Posted by on December 10th, 2018

I am Shinichi Morita, a postdoctoral researcher in Teruyuki Niimi’s lab at the National Institute for Basic Biology, Japan (Fig. 1A, B). Our research interests focus on the evolutionary novelties that insects have acquired, and how various insect morphologies have arisen during evolution (Fig. 1C-P).     Beetle horns are thought to be an evolutionary[…]

The people behind the papers – Chaitanya Dingare and Virginie Lecaudey

Posted by on December 5th, 2018

This interview, the 52nd in our series, was the first to be published in Development. We’re aiming for one interview per issue, and will continue to put them up here (once the issue has closed).    During teleost fertilisation, sperm fertilises the oocyte through the micropyle, a channel traversing the vitelline membrane at the animal[…]

November in preprints

Posted by on December 4th, 2018

Welcome to our monthly trawl for developmental biology (and related) preprints.  This month’s haul includes a potful of plant development, new ways to mend broken hearts, an Alexa in the lab, and three preprints from Development’s recently appointed Editor Cassandra Extavour. The preprints were hosted on bioRxiv, PeerJ, and arXiv. Let us know if we missed anything, and use[…]

The reported birth of CRISPR-edited humans: reactions from the field

Posted by on November 29th, 2018

One scientific story has dominated the news this week: the first report of CRISPR-edited human babies being born. In an associated Node post, we’ve collected the most useful links we could find surrounding the story, and here we reached out to members of the community for their perspectives. Some responses are hopefully still coming in[…]

The reported birth of CRISPR-edited humans: useful links

Posted by on November 29th, 2018

One scientific story has dominated the news this week: the first report of CRISPR-edited human babies being born. The story’s scientific and ethical aspects stirred up heated debate, as did its means of delivery: rather than a published paper, the story broke with reports of clinical trial documents and then a YouTube video from lead[…]

Immature Cells Zap Around Before Settling Down

Posted by on November 28th, 2018

The story is based on the paper Mechanosignalling via integrins directs fate decisions of pancreatic progenitors, published in Nature, 28 November 2018 Stem cells are already being used in combating previously untreatable diseases. Nevertheless, stem cells are not delivering their full potential because the production of specific cell types from stem cells cannot yet be managed. Researchers[…]

A scientific face for the fifty

Posted by on November 28th, 2018

Here at The Company of Biologists we’ve been debating the Bank of England’s decision to put a scientist on their new £50 note (the highest denomination note in England). The scientist must be deceased (only the Queen can grace notes while still alive) and ‘have shaped thought, innovation, leadership or values in the UK’. Each of[…]