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NIH launches competition to develop human eye tissue in a dish

Posted by on June 21st, 2017

3-D Retina Organoid Challenge to spur breakthroughs in treating blinding diseases The National Eye Institute (NEI), part of the National Institutes of Health, has opened the first stage of a federal prize competition designed to generate miniature, lab-grown human retinas. The retina is the light- sensitive tissue in the back of the eye. Over the[…]

In Development this week (Vol. 144, Issue 12)

Posted by on June 21st, 2017

Here are the highlights from the current issue of Development:   Btbd7 branches out across multiple organs Dynamic changes in epithelial cell-cell adhesion and motility are crucial for branching morphogenesis – the process by which highly branched epithelial organs, such as the lung and kidney, grow and develop from a simple epithelial bud. Although many[…]

One more day to vote!

Posted by on June 20th, 2017

Our image competition for a future Development cover is still live: voting closes tomorrow at 13.00 GMT! Click here to vote and find out more about the images   (No Ratings Yet) Loading…

Diversity, Connections and Collaboration during Embryology 2017 at the MBL

Posted by on June 19th, 2017

Things are in full swing at MBL in the 2017 Embryology course, we are already one third of the way through! The first week we learned about echinoderms and C. elegans with a side of Tardigrade and this past we focused on zebrafish and Xenopus with axolotl. The atmosphere of the past two weeks has[…]

Why do we need to understand the structure of the Enteric Nervous System?

Posted by on June 16th, 2017

Insight into the organizational structure of a growing tissue is imperative for understanding its development and function. Structure can reveal the systematic steps undertaken towards making specific positional and cell fate choices/decisions. A well-defined structure helps to dissect the complexity underlying the networks that form as the tissue develops. It helps to elucidate the foundation[…]

Multiple stem cells, population asymmetry and position-dependent heterogeneity emerge as common features of a niche for Drosophila Follicle Stem Cells and mammalian Intestinal Stem Cells

Posted by on June 16th, 2017

A discussion of “Alternative direct stem cell derivatives defined by stem cell location and graded Wnt signalling,” Nat Cell Biol, 2017. 19(5): p. 433-444.   We have recently revised the model of Follicle Stem Cell (FSC) organization in the Drosophila ovary, showing that there is a much larger population of stem cells than formerly realized, that[…]

Getting to know us – an article about the Node and social media

Posted by on June 15th, 2017

Last year we were approached by Andreas Prokop of The University of Manchester (who is also Communications Officer of the British Society for Developmental Biology), with an offer to write a paper on our experiences of running the Node and using social media to build scientific networks. We – that is Aidan Maartens (the Node’s Community[…]

The Day of a 2017 Embryology Student

Posted by on June 12th, 2017

Daily life changes when you set foot in Woods Hole. There is a beauty in your surroundings and energy in the air that invigorates you. The days are long (8am to 2 or 3 am most days!) and we have a full schedule but we are all so excited to be here – to learn[…]

The people behind the papers: Lijun Chi and Paul Delgado-Olguin

Posted by on June 9th, 2017

Development of the placental vasculature – known as the labyrinth – is critical for foetal development. Today’s paper comes from the most recent issue of Development and addresses the signalling events involved in placental vascular maturation. We caught up with lead author Lijun Chi and her PI Paul Delgado-Olguin of the Hospital for Sick Children and University[…]

2017 MBL Embryology Course underway at Woods Hole!

Posted by on June 8th, 2017

Today marks Day 3 of the Embryology: Concepts & Techniques in Modern Developmental Biology course (http://www.mbl.edu/education/courses/embryology/) at the Marine Biological Laboratories in Woods Hole, MA (http://www.mbl.edu/). 24 students along with faculty, teaching assistants and course assistants arrived over the weekend to embark on a life changing summer experience. Since my days in undergraduate research in[…]