Emergence of functional polarity in a tubular epithelium
Epithelial tubes often have a functional polarity written along their proximo-distal (P-D) axis, with different segments of specialised cell-types carrying out distinct physiological activities. With a handful of notable exceptions, we know very little about how P-D axes and segment-specific differentiation are regulated during organogenesis.
The major objective of this project is to understand the molecular and cellular mechanisms that pattern and maintain functional polarity along the P-D axis in a structurally simple, but functionally sophisticated epithelial tube: the insect renal tubule.
The project will be carried out in the laboratory of Barry Denholm (Biomedical Sciences, University of Edinburgh)
About the lab and department:
Further information about the project and details of how to apply:
Completed application form along with your curriculum vitae should be sent to our PGR student team at RDSVS.PGR.Admin@ed.ac.uk
Download application and reference forms via: https://www.ed.ac.uk/roslin/postgraduate/bbsrc-eastbio-dtp
Closing Date: 5thDecember 2018