An NIH-funded postdoctoral position is available in Jianbo Wang’s lab at the Univ. of Alabama at Birmingham. We study how shape forms during embryogenesis, and how aberrant shape formation leads to congenital birth defects. The process of shape formation is known as morphogenesis, and is regulated in part by the planar cell polarity (PCP) pathway. PCP is a unique signaling mechanism that coordinates cellular polarity and regulates dynamic, directional cell behavior. Our studies involve multi-disciplinary approaches including genetic, imaging, cell biology and biochemistry; and use multiple model organisms including the mouse, chick and Xenopus. Our goals are to 1) uncover novel mechanisms and logic of PCP signaling; 2) elucidate the role of PCP in cardiovascular, skeletal and neural development; and 3) investigate how human PCP gene variants contribute to congenital disorders.
We are looking for highly motivated applicants with training in Developmental Biology, Genetics, Cell Biology or a related discipline. To apply, please email your CV, a description of previous research and contact information for three references to firstname.lastname@example.org.