An NIH R01-funded postdoctoral position is available in the laboratory of Dr. Beth Roman in the Department of Human Genetics at the University of Pittsburgh. We study the interplay between molecular and biomechanical pathways in the control of endothelial cell behavior and vascular development and disease. Our primary focus is on endothelial bone morphogenetic protein (BMP)/ALK1 signaling, which is disrupted in the genetic vascular disorder, hereditary hemorrhagic telangiectasia (HHT). We are looking for a motivated scientist to lead studies exploring the molecular, cellular, and biomechanical basis for BMP ligand requirements in HHT, using zebrafish and primary endothelial cell culture models.
Qualified candidates must have a PhD in a relevant field, a strong publication record, and excellent oral and written English communication skills. Expertise in molecular biology and cell culture is required. Experience with confocal microscopy and the zebrafish model is strongly preferred. Interested candidates should send a brief cover letter summarizing scientific accomplishments and outlining motivation for this position; a full CV; and full contact information for three professional references to Dr. Beth Roman at firstname.lastname@example.org.
The University of Pittsburgh is a collaborative, collegial environment for biomedical research. Our laboratory is part of a large, interactive zebrafish community, and we are affiliated with the Heart, Lung, and Blood Vascular Medicine Institute (VMI). The VMI offers numerous opportunities for collaboration and provides access to competitive T32 postdoctoral positions.
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