the community site for and by developmental biologists

Using the mouse to model human disease: increasing validity and reproducibility

Posted by on February 3rd, 2016

This editorial by Monica J. Justice and Paraminder Dhillon was first published in Disease Models & Mechanisms.   ABSTRACT Experiments that use the mouse as a model for disease have recently come under scrutiny because of the repeated failure of data, particularly derived from preclinical studies, to be replicated or translated to humans. The usefulness of[…]

Postdoctoral position, Cutaneous Biology Research Center, Harvard Medical School.

Posted by on February 3rd, 2016

Postdoctoral position to study organogenesis and regeneration using the mouse hair follicle as a model system. The Morgan lab exploits genetically engineered mice to study the role of the mesenchyme in the development and regeneration of the hair follicle with a focus on how feedback between the epithelial and mesenchymal compartments is modified to regulate[…]

Postdoctoral Research Associate position in Cell Biology of Neuronal Differentiation – University of Manchester

Posted by on February 3rd, 2016

Applications are invited for a highly motivated post-doctoral research associate to join the laboratory of Dr Raman Das in the Faculty of Life Sciences at the University of Manchester, UK. The successful candidate will exploit cutting-edge live tissue imaging techniques to dissect the cell biological mechanisms regulating establishment of neuron polarity and axon extension during[…]

Green Glow the Salamanders

Posted by on February 3rd, 2016

This is an terrific Shelf Life video made by Erin Chapman at the American Museum of Natural History. It features our work on a symbiosis between the classic model salamander Ambystoma maculatum and its algal symbiont, Oophila amblystomatis.   (+2 rating, 2 votes)Loading…

21st Century Journal Clubs

Posted by on February 2nd, 2016

Does anyone have 21st century ideas on how to run a diverse (not just developmental biology) departmental journal club? (+2 rating, 2 votes)Loading…

Growth and regeneration – what’s the common thread?

Posted by on February 2nd, 2016

Last week, I attended the Keystone Symposium “Molecular and cellular basis of growth and regeneration”. This outstanding meeting was the second incarnation of a Keystone meeting on regeneration; the first having been held in 2012 – Development reviewed it here. The expansion in scope of this year’s meeting to encompass both growth and regeneration was,[…]

In Development this week (Vol. 143, Issue 3 )

Posted by on February 2nd, 2016

Here are the highlights from the current issue of Development:   New insights into human neural crest induction Human neural crest (NC) cells are the precursors for a wide range of ectodermal and mesenchymal cell derivatives. Due to the inherent difficulties associated with early human embryonic studies, it is currently unclear exactly when NC cells[…]

Abigail Tucker: the first to be awarded the BSDB Cheryll Tickle medal

Posted by on February 1st, 2016

As reported earlier last year, the BSDB has introduced the Cheryll Tickle Medal, which will be awarded annually to a mid-career, female scientist for her outstanding achievements in the field of Developmental Biology. The BSDB is proud to announce the inaugural awardee Prof. Abigail Saffron Tucker. The medal was handed over to Abigail at the[…]

This month on the Node- January 2016

Posted by on February 1st, 2016

We’ve had a busy start to 2016 on the Node! Check out this round-up of new content, and remember to check our Jobs page for new opportunities, and our Events page to keep up to date with conference and course deadlines.   Research –What can zebra finches tell us about pluripotency? Raj posted about early[…]