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Posted by the Node Interviews, on 5 April 2018
Development and homeostasis depend crucially on the maintenance of cell identity, and in gamete-producing tissues the somatic/germline distinction is paramount. A recent paper in Development explores how cell identity is ...Posted by frankschnorrer, on 4 April 2018
Muscle building: bridging molecular order to macroscopic morphogenesis PHD2018-11 (PDF link)Posted by the Node, on 4 April 2018
One of the most talked about preprints this month was a corrigendum to that Nature Methods paper reporting widespread off-target mutations following CRISPR-Cas9 editing in mice. The paper was challenged quickly on ...Posted by Patrick Lemaire, on 3 April 2018
The project: Single-cell approaches are revolutionizing developmental biology. We can now trace in time the behavior of each cell in a live developing organism (1). In parallel, single-cell transcriptomics and ...