the community site for and by developmental biologists

The people behind the papers – Rémi-Xavier Coux & Ruth Lehmann

Posted by on April 5th, 2018

Development and homeostasis depend crucially on the maintenance of cell identity, and in gamete-producing tissues the somatic/germline distinction is paramount. A recent paper in Development explores how cell identity is secured in the Drosophila ovary by studying the function of the conserved tumour suppressor L(3)mbt. To find out more about the story, we caught up with first author Rémi-Xavier[…]

Collaborative PhD position at the Turing Centre in Marseille

Posted by on April 4th, 2018

Muscle building: bridging molecular order to macroscopic morphogenesis   PHD2018-11 (PDF link) (No Ratings Yet)Loading…

March in preprints

Posted by on April 4th, 2018

One of the most talked about preprints this month was a corrigendum to that Nature Methods paper reporting widespread off-target mutations following CRISPR-Cas9 editing in  mice. The paper was challenged quickly on bioRxiv, and four days after the corrigendum went up, it was retracted, as reported by Retraction Watch! Blink and you’ll miss it. Otherwise this month[…]

PhD project on membrane trafficking dynamics during epithelial polarization

Posted by on April 3rd, 2018

The newly established Collaborative Research Center 1348 “Dynamic Cellular Interfaces: Formation and Function” at the University of Münster, Germany, invites applications for a   PhD Position (salary level 13 TV-L, 65%) in the area of Membrane trafficking dynamics during epithelial polarization This fixed-term position is available from the earliest possible date for three years. The[…]

PhD position: Single-cell elucidation of the evolution of an embryonic transcriptional programme

Posted by on April 3rd, 2018

The project: Single-cell approaches are revolutionizing developmental biology. We can now  trace in time the behavior of each cell in a live developing organism (1). In parallel, single-cell transcriptomics and genomics gives access to the transcriptional state of each cell (2). Combination of these two approaches promises to unravel how genomic information translates into individual[…]