Workshop “Membrane Traffic at the Synapse. The Cell Biology of Synaptic Plasticity”
Posted by Catarina Vicente, on 1 July 2015
It is now evident that synaptic function relies on core components of the intracellular membrane trafficking machinery to support key aspects of neurotransmitter vesicle cycling and postsynaptic receptor translocation. On the other hand, synaptic membranes are endowed with specific molecular tools tailored to fulfill the unique demands of synaptic transmission, such as the tight temporal and spatial regulation of membrane fusion, or its coupling to synaptic activity. This workshop will bring together these concepts, in an effort to integrate synaptic and neuronal physiology within the realm of cell biology. It will emphasise the multidisciplinary aspect of modern neuroscience research and the development of new experimental techniques, including cutting-edge imaging and electrophysiological approaches, together with powerful genetic manipulations to assess the role of individual molecules in complex behaviors and their implication in cognitive disease.