Postdoctoral Associate – Cell Polarity and Development of the Inner Ear

How do we perceive sounds, gravity or head movements? It all starts during development, when sensory cells in the inner ear acquire a crown of motion detectors known as the stereocilia bundle. The Tarchini laboratory investigates the molecular mechanisms that corral and layer stereocilia into a functional bundle, a highly polarized architectural process that, when defective, results in deafness. (http://tarchini-lab.org).

We are seeking a Postdoctoral Associate interested in dissecting how G protein signaling controls and coordinates two features essential for hearing and balance ability: 1) the striking alignment of hair cells along the epithelial plane (planar polarity), and 2) the staircase-like architecture of the motion-sensor compartment of hair cells, the stereocilia bundle.

Required qualifications include a recently obtained PhD in Developmental or Cell Biology, Neuroscience or a related field. Expertise with inner ear Biology and mouse genetics is desired but not required

The Jackson Laboratory (http://www.jax.org) in Bar Harbor, Maine, USA, is recognized internationally for its excellence in research, unparalleled mouse resources, outstanding training environment, and exceptional core services – all within a spectacular setting adjacent to Acadia National Park. The Tarchini lab is currently funded with an R01 grant from the National Institute on Deafness and Other Communication Disorders (NIH NIDCD; https://www.nidcd.nih.gov) and support from The Jackson Laboratory.

To apply, please submit (1) a short cover letter describing past research accomplishments and research interests, (2) a current CV, and (3) the contact information of three references. Please send application to: basile.tarchini@jax.org, or apply online at https://jax.silkroad.com/epostings/index.cfm?fuseaction=app.dspjob&jobid=220648&company_id=15987&version=3&jobBoardId=3345

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