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Postdoc position: Regulation of intestinal proliferation in Drosophila

Posted by , on 9 June 2017

Closing Date: 15 March 2021

A postdoctoral position is available to study the extrinsic modulation of intestinal proliferation in the research group of Golnar Kolahgar at the Department of Physiology, Development and Neuroscience at the University of Cambridge. The candidate is expected to hold a PhD in cellular, molecular or developmental biology.

Our goal is to identify the components of the extracellular space that contribute to maintaining and remodelling the adult intestine in response to various physiological conditions. We use the genetically tractable Drosophila gut as a paradigm to investigate cell fate decisions in vivo (e.g. Kolahgar et al, Dev Cell, 2015; Suijkerbuijk et al, Curr. Biol, 2016). The aim of this project is to explore how integrin signalling promotes intestinal stem cell proliferation and contributes to gut plasticity, using a combination of Drosophila genetics, lineage tracing and clonal analysis, confocal imaging and whole genome sequencing, thus experience with one or several of these techniques is required.

The post is funded for an initial period of 3 years.

For more information and to apply, follow this link: http://www.jobs.cam.ac.uk/job/13950/

Informal enquiries to Golnar Kolahgar (gk262 [at] cam.ac.uk)

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