Postdoctoral Fellow: genetic instability in human stem cells and development

A fully funded Postdoctoral position is available in the Department of Medicine, Washington University in St. Louis, St. Louis, MO, United States. The Batista Lab (https://batistalab.org/) is seeking a postdoctoral fellow to study the consequences of genetic instability in human stem cells, disease, and cancer, using human pluripotent stem cells and targeted differentiation approaches as a primary working model. Our goal is to determine how DNA and RNA instability lead to tissue failure and cancer, and to develop novel therapeutic approaches to mitigate and treat deleterious phenotypes that arise in patients with impaired DNA and RNA maintenance pathways. Some recent examples of our research include Jeong et al, Science 2023; Vessoni et al, JCB 2021, Munroe et al Hepatology 2020. This project will likely involve human stem cell differentiation assays, protein analysis, single-cell RNA-Sequencing, CRISPR genome editing, and general molecular biology techniques.

The successful candidate should have a good publication record, and strong background in molecular biology and cell biology. Interested candidates should submit their curriculum vitae, statement of research interests and contact information of three references via e-mail to Dr. Luis Batista (lbatista@wustl.edu).