Postdoc in molecular control of cardiac development and regeneration

Research laboratory presentation The Marín-Juez laboratory, at the Centre de recherche Azrieli du CHU Sainte-Justine, is recruiting a postdoctoral fellow (up to 5 years fully funded position). Our laboratory is interested in the cellular and molecular mechanisms regulating cardiac regeneration and development. The successful applicant will join the Marín-Juez laboratory at the CHU Sainte-Justine Research Center, where s/he will have access to state-of-the-art facilities and technology platforms including Advanced imaging platform (light-sheet, spinning-disc confocal, multiphoton, STED super-resolution, etc.), genomics (DropSeq, 10x, Illumina Novaseq, Visium), IPSC Cell Reprograming and bioinformatics platforms. CHU Sainte-Justine Research Center provides a thriving scientific environment where the successful applicant will have the opportunity to work with multidisciplinary scientific teams and to collaborate with talented clinicians and researchers. Research project description We have previously identified coronary network regeneration as a critical determinant of heart regeneration (Marín-Juez et al., PNAS 2016; Wang et al., Development 2024). Our work has uncovered mechanisms governing coronary network replenishment, including the formation of a vascular scaffold that supports cardiomyocyte regeneration and mediates coronary-epicardial interactions (Marín-Juez et al., Dev Cell 2019; El-Sammak et al., Circ Res 2022). Building on these findings, we now aim to elucidate how the cardiac endothelium, epicardium, and immune system components cooperate to regulate tissue replenishment, as well as the specific mechanisms underlying their roles in cardiomyocyte regeneration. Required training and profile We are looking for candidates with a Ph.D. in the biological sciences and laboratory experience in tissue repair/regeneration, cellular, molecular biology, or genetics. Previous experience working with zebrafish, imaging and histology are highly valued but not essential. Candidates with experience in confocal/light-sheet imaging and/or genome engineering are strongly encouraged to apply. Preference will be given to applicants with excellent collaborative and communication skills. Project title: Molecular control of cardiac development and regeneration Start date: 2025 The Marín-Juez lab and the CHU Sainte-Justine Research Center subscribe to the principle of equal access to opportunities and encourage women, members of visible and ethnic minorities, persons with disabilities and Indigenous people to apply. Submit your application Candidates must send the required documents before 30/04/2025 to Rubén Marín Juez at ruben.marin.juez.hsj@ssss.gouv.qc.ca Please provide: √ Curriculum vitæ √ Cover letter √ References (2 or 3)