A 3-years-PhD position to study the development of the human eye

A 3-years-PhD position is available at the Chédotal Lab at the Vision Institute in Paris.
The goal of the PhD project will be to describe the organization of the developing human eye and characterize molecular and cellular mechanisms underlying human retinogenesis. We propose to revisit eye formation combining modern and innovative single-cell molecular and 3D imaging approaches on human embryo/fetal eye samples. Data from light sheet fluorescent microscopy (LSFM), spatial transcriptomics and in situ sequencing will be incorporated into one scaffold to provide a comprehensive 3D map of human retinogenesis. The project will provide significant and detailed insights into human ophthalmology, generating the first reference map of human retina development. It will further contribute to the Human Cell Atlas initiative. The thesis will be directed by Dr Alain Chédotal.
An experience in bioinformatics and transcriptomics or 3D imaging would be a plus but is not required.
Candidates should hold a diploma or a master’s degree in Neuroscience, Developmental Biology, Microscopy or Bioinformatics
They may send their application (in a PDF-format) to Dr Alain Chédotal (alain.chedotal@inserm.fr), including a CV and contact information for two references.

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