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About: hiroueda

Dr. Hiroki R. Ueda was born in Fukuoka, Japan, in 1975. He graduated from the Faculty of Medicine, the University of Tokyo, in 2000, and obtained his Ph.D in 2004 from the same university. While an undergraduate student, he worked as a research assistant on a biological simulation system project at Sony Computer Science Laboratories. While a graduate student, he next went on to work as a researcher from 2000 and then group leader from 2002 at Yamanouchi Pharmaceutical Co. He was appointed as a team leader of laboratory for systems biology at RIKEN Center for Developmental Biology (CDB) from April, 2003 and promoted to be a project leader at CDB from September, 2009. He was also appointed as a manager of Functional Genomics Unit at the CDB from October, 2004 - March, 2013, and a head of laboratory for synthetic biology at RIKEN Quantitative Biology Center (QBiC) from April, 2011. He became a professor of Graduate School of Medicine and Faculty of Medicine of the University of Tokyo from October, 2013. He also became a visiting professor in Tohoku University in April, 2005 - March, 2006, Tokushima University from April, 2005, National Institute of Genetics from April, 2010 - March, 2013, Graduate School of Medicine and Faculty of Medicine of the University of Tokyo from October, 2012 - September, 2013, and an invited professor of biology in Osaka University from April, 2006, and an invited professor of mathematics in Kyoto University from April, 2009 - March, 2013. He identified system-level network structure of mammalian circadian clocks. For this discovery, He received Tokyo Techno Forum 21, Gold Medal (Tokyo Techno Forum 21, 2005), Young Investigator Awards (MEXT, 2006) and IBM Science Award (IBM, 2009). He recently solved the fundamental problem in chronobiology on the underling mechanism of singularity behavior of circadian clock that had been unsolved for more than 30 years. For this discovery, he received a Young Investigator Promotion Awards (Japanese Society for Chronobiology, 2007). He also recently discovered temperature-insensitive reaction in mammalian circadian clock, which is related to a long-standing problem, "temperature-compensation" of circadian clock. For this discovery, he received Tsukahara Award (Brain Science Foundation). He invented diagnostic method of body time and rhythm disorders, which opens up the new possibility of chronotherapy. For this invention, he received Japan Innovator Awards (Nikkei Business Publications Inc. 2004). He also recently developed the new method, CUBIC for whole-body/whole-brain clearing and imaging with single-cell resolution), for which he received Teiichi Yamazaki Awards (2015). His current research interests include the realization of organism-level systems and synthetic biology and its application to the biological timings problems.

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Posted by on October 23rd, 2015

Dimitri Perrin3, Shimpei I. Kubota1,2, Kazuki Tainaka1,2 & Hiroki R. Ueda1,2,4* 1Department of Systems Pharmacology, The University of Tokyo, Tokyo, Japan. 2CREST, Japan Science and Technology Agency, Saitama, Japan. 3School of Electrical Engineering and Computer Science, Science and Engineering Faculty, Queensland University of Technology, Brisbane, Australia. 4Laboratory for Synthetic Biology, RIKEN Quantitative Biology Center, Osaka,[…]