the community site for and by developmental biologists

About: hkugler


Posts by hkugler:

Modeling stem cell population dynamics

Posted by on December 23rd, 2011

Many tissues and organs contain self-renewing stem cell populations that are crucial for their maintenance. Synthesizing the relative effects of anatomical constraints, cell proliferation dynamics and cell fate specification on the overall stem cell population dynamics is challenging, and so we reasoned that dynamic computational models that have the potential to systematically manipulate different influences[…]