the community site for and by developmental biologists

About: Joseph Barry

I am a computational biologist working in John Quackenbush's group at Dana-Farber Cancer Institute in Boston. I specialize in finding biologically interesting patterns in large imaging datasets.

Posts by Joseph Barry:

Applying tandem timers to measure signalling and gene expression dynamics in developing embryos

Posted by on January 11th, 2016

The signalling systems that conduct the orchestra of embryonic development are fantastically complex and dynamic. We owe much of our knowledge of in vivo signalling dynamics to advances in microscopy and protein tagging with fluorescent reporters that have allowed visualization of signalling proteins. Looking forward, however, it is clear that simply analyzing the localization patterns[…]