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developmental and stem cell biologists

Kristen Panfilio

I am the Professor of Molecular Genetics in the Institute of Biology, University of Hohenheim, Germany. My lab has the twin aims of understanding the cell and tissue basis of animal development, primarily through advanced live cell imaging approaches, and of elucidating the regulatory basis for species-specific development and physiology, through the framework of functional genetics, comparative 'omics, and molecular evolution. Our primary research system is the protective extraembryonic (EE) tissues of insects: the serosa and amnion. These fascinating tissues are a synapomorphy of the insects, are essential for development, and have been implicated in the radiation and evolutionary success of the insect lineage. Studying epithelial tissue biology in this system allows for a natural integration that spans macroevolution, developmental genetics, cellular physiology, and tissue morphogenesis. In particular, live imaging of EE morphogenesis is addictive, and I love playing with all sorts of microscopes and (slowly!) developing new transgenic imaging lines. I've also become a genome junkie, and have been active since 2012 in the international i5K community for de novo genome sequencing and comparative genomics in arthropods. This has begun to stretch our research foci to post-embryonic eco-evo-devo phenomena as well. Additional key words: cell/ tissue architecture; RNAi; red flour beetle (Tribolium castaneum); milkweed bug (Oncopeltus fasciatus); transcription factors; lineage-specific genes

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Posts by Kristen Panfilio

Postdoc in polyploidy: from cell physiology to tissue-scale effects of nuclear structure

Posted by , on 4 January 2021

A postdoctoral research position is available in the group of Dr. Kristen Panfilio at the University of Warwick, UK, to join our BBSRC-funded project on how polyploid nuclear structure influences ...

Senior Research Technician in the Panfilio Lab, University of Warwick, UK

Posted by , on 5 August 2019

School of Life Sciences, University of Warwick, UK   A full-time, twelve-month Senior Research Technician position is available for an immediate start in the laboratory of Dr Kristen Panfilio, for ...

Postdoc: Comparative epithelial morphogenesis

Posted by , on 23 July 2016

From autumn 2016, a postdoctoral research position is available in the Panfilio lab to investigate morphogenesis of the insect extraembryonic (EE) membranes. These simple epithelia are highly dynamic in their ...

Evo-Devo PhD Position (Molecular Evolution) in Cologne, Germany

Posted by , on 31 December 2013

From early 2014, a PhD studentship is available in the Panfilio lab to investigate hypotheses of macroevolutionary change in gene function.  The aim is to address the evolution of the ...

Comparative epithelial morphogenesis research positions (PhD, Postdoc)

Posted by , on 26 October 2011

From early 2012, a PhD studentship and a postdoctoral position are available in the Panfilio lab (in Cologne, Germany) to investigate morphogenesis of the insect extraembryonic membranes.  As protective covers ...

Recent jobs by Kristen Panfilio

Positions (PhD, Postdoc) in insect developmental genetics and molecular evolution

Posted by , on 26 September 2023

  From early 2024, a PhD studentship and a postdoctoral position are available in the Panfilio Lab at the University of Hohenheim, Germany. We investigate gene expression and function in embryos (e.g., RNA-seq, RNAi, molecular cloning), with a strong live-cell imaging microscopy component, embedded in a framework of comparative genomics and environmental interactions. Our research […]

Ph.D. position on epithelial physiology and nuclear structure

Posted by , on 21 April 2021

Our lab has a Ph.D. project available on “The role of polyploidy across the lifespan of epithelial tissues“.  This is a competition-funded project available through the Midlands Integrative Biosciences Training Partnership (MIBTP), which emphasizes quantitative skills and interdisciplinary training, available to UK-based and international students alike.  The application deadline is 6th May 2021. Epithelial tissues […]

Senior Research Technician in the Panfilio Lab, University of Warwick, UK

Posted by , on 12 April 2021

A full-time Senior Research Technician position is available for an immediate start in the laboratory of Dr. Kristen Panfilio, for molecular genetics, cell biology, and lab management tasks to support investigations of insect embryology for basic biomedical research. The position is planned for two years in the first instance. Our lab uses a range of imaging, […]