Posted by Sigolène Meilhac, on 10 November 2015
In the Institut Imagine and Institut Pasteur, Paris France, the laboratory of Sigolène Meilhac is interested in the mechanism of heart morphogenesis. We focus on the regulation of cell behaviour ...Posted by Sigolène Meilhac, on 9 July 2024
The heart functions in two parallel but asymmetric circuits, in which the right and left ventricles drive the pulmonary and systemic circulations, respectively. In the heterotaxy syndrome, abnormal left-right patterning of the embryo leads to a spectrum of severe structural heart defects, the heterogeneity of which remains puzzling. Whereas the molecular cascade breaking the bilateral […]
Posted by Sigolène Meilhac, on 6 December 2023
The heart functions in two parallel but asymmetric circuits, in which the right and left ventricles drive the pulmonary and systemic circulations, respectively. In the heterotaxy syndrome, abnormal left-right patterning of the embryo leads to a spectrum of severe structural heart defects, the heterogeneity of which remains puzzling. Whereas the molecular cascade breaking the bilateral […]
