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Sophie Astrof

Sophie Astrof received her Bachelor’s and Master’s degrees in Biochemistry from Brandeis University in 1995 in the laboratory of Dr. Abeles. She received her Ph.D. degree in Virology from Harvard University in 2000 in the laboratory of Dr. John A.T. Young. Consequently, she did her postdoctoral work with Dr. Richard Hynes at MIT where she developed her interest in extracellular matrix biology and cardiovascular development. Astrof lab investigates mechanisms by which cell-extracellular matrix interactions orchestrate cardiovascular development and how alterations in these interactions cause congenital heart disease.


Posts by Sophie Astrof

Postdoc position

Posted by , on 4 January 2013

A postdoctoral position is available in the laboratory of Dr. Sophie Astrof to study roles of cell-extracellular matrix interactions in cardiovascular development and disease using mouse model system. The research ...

Recent jobs by Sophie Astrof

Postdoc in cardiovascular development

Posted by , on 8 July 2021

We are looking for a motivated postdoctoral fellow to study mechanisms by which cell-extracellular matrix (ECM) interactions regulate cardiovascular development and how dysfunctional ECM signaling results in congenital heart disease. In vivo projects in the lab focus on the role of ECM in the regulation of vascular progenitor cell fate specification and cardiovascular morphogenesis with […]