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developmental and stem cell biologists

Uwe Töpfer

Posts by Uwe Töpfer

AdamTS matrix metalloproteases mediate basement membrane heterogeneity required for organ elongation

Posted by , on 4 July 2024

Basement membranes (BMs) are thin, specialized extracellular matrices that surround most tissues and organs (Jayadev and Sherwood, 2017). These meshworks serve as scaffolds for cell adhesion, influencing cell signaling, cell ...

Joint International GfE/DSDB Meeting – Meeting report

Posted by , on 8 May 2024

What better place to hold a conference than a castle? Well, the 25th Conference of the German Society for Developmental Biology (GfE) was held in the historic castle of Osnabrück ...

Basement membrane mechanical properties

Posted by , on 20 May 2022

Extrinsic forces have an underestimated impact on shaping tissues and organs. Extracellular matrixes surround tissues and provide the cells with mechanical stimuli to drive morphogenetic processes.  A specialized extracellular matrix ...