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Displaying posts in the category: Highlights [Clear Filter]

From Image to Insight – Morphogenesis Meets Data Science

Posted by on September 26th, 2020

A wave of innovations is advancing data-driven computational analysis and machine learning – time for developmental biologists to hop on the surf board! This post, inspired by our recent data-driven work on lateral line morphogenesis, provides a brief primer on key concepts and terms. written by Jonas Hartmann & Darren Gilmour From machine translation to[…]

August in preprints

Posted by on September 1st, 2020

Welcome to our monthly trawl for developmental biology (and related) preprints.  The preprints this month are hosted on bioRxiv and arXiv – use these links to get to the section you want.   Developmental biology | Patterning & signalling | Morphogenesis & mechanics | Genes & genomes | Stem cells, regeneration & disease modelling | Plant development Evo-devo & evo[…]

July in preprints

Posted by on August 4th, 2020

Welcome to our monthly trawl for developmental biology (and related) preprints.  This month features a host of preprints on human development at the single cell level (perhaps all submitted in time for Development’s September meeting?), plus insights into how butterflies make clear wings and how worms achieve meiosis, and a whole lot more. Preprints hosted[…]

Retracting sheaths and words

Posted by on July 17th, 2020

My mentor, Bruce Appel, emphasizes the importance of communicating science clearly and precisely. Consequently, I have watched my peers and myself deliver ever-improving talks, posters, and manuscripts during our time in the lab. I think that many people in science appreciate that clear communication is essential for others to be able to interpret findings and[…]

June in preprints

Posted by on July 1st, 2020

Welcome to our monthly trawl for developmental biology (and related) preprints.  Preprints hosted on bioRxiv and arXiv, use these links to get to the section you want.   Developmental biology | Patterning & signalling | Morphogenesis & mechanics | Genes & genomes | Stem cells, regeneration & disease modelling | Plant development Evo-devo & evo Cell biology Modelling Tools &[…]

Now we need arrest… A long journey into the end-of-flowering

Posted by on June 29th, 2020

By Tom Bennett & Catriona Walker   25th May 2020: Publication TB: The joy of seeing an article finally published is always slightly tempered by the long-drawn out process of peer review, re-writing, re-submission, re-review, proof-reading, required to get to that point. But the publication of our article ‘Auxin export from proximal fruit drives arrest[…]

The story of my heart, from the bottom of my heart (says the Zebrafish)

Posted by on June 23rd, 2020

I started off as quite little—just one cell, in fact. No heart, no brain, no blood flowed in me and yet, somehow I found the motivation in me to divide. One me made two and two mes made four, till many tiny mes made me a full-fledged embryo with a heart full of hope. As[…]

Pregnancy complications in assisted reproduction linked to a specific process

Posted by on June 9th, 2020

A Press Release from the University of Pennsylvania School of Medicine – see the Development paper by Lisa Vrooman, Marisa Bartolomei and colleagues here. An experimental study from researchers in the Perelman School of Medicine at the University of Pennsylvania links a specific procedure – embryo culture – that is part of the assisted reproduction[…]

Research Highlight #5: Leukemic stem cells from iPSCs

Posted by on June 9th, 2020

Today let’s delve into a curious case involving induced pluripotent stem cells (iPSCs) and leukemic stem cells (LSCs). Most blood cells derived from iPSCs are unable to engraft in immunodeficient mice. However, Wesely and colleagues observed an exceptionally high engraftment efficiency of cell lines derived from an individual affected by acute myeloid leukemia (AML). In[…]

Catch Me if You Can: An elusive underpinning for Arx(GCG)10+7-mediated apoptosis in X-linked infantile spasms syndrome

Posted by on June 3rd, 2020

This post highlights the approach and finding of a new research article published by Disease Models and Mechanisms (DMM). This feature is written by Olivia Howell as apart of a seminar at The University of Alabama (taught by DMM Editorial Board member, Prof. Guy Caldwell) on current topics related to use of animal and cellular[…]