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Displaying posts in the category: Highlights [Clear Filter]

Off and On: it’s more complicated than we thought.

Posted by on January 23rd, 2020

We learn fairly early on when becoming biologists that both development and an organism’s response to environmental stressors require turning the right set of genes on in the right cells, at the right time. Clearly, for “on” to be meaningful, other genes have to be “off,” and many disordered conditions are associated with misexpression of[…]

the Node’s 2019 highlights

Posted by on January 7th, 2020

A new year is a good opportunity to look back on the one just passed, and whether you’re a Node regular or new to us, this selection of our 2019 highlights will hopefully be of interest, particularly if you’re interested in contributing something and looking for inspiration. We are a community site for and by[…]

December in preprints

Posted by on January 3rd, 2020

Welcome to our monthly trawl for developmental biology (and related) preprints.  Here’s the last cache of preprints of 2019 – happy preprinting in 2020! They were hosted on bioRxiv and arXiv. Let us know if we missed anything. Use these links to get to the section you want:   Developmental biology | Patterning & signalling | Morphogenesis & mechanics | Genes[…]

12 GIFs of Christmas 2019

Posted by on December 20th, 2019

In keeping with a time-honoured tradition, we recently flooded Twitter with 12 beautiful developmental biology GIFs. They came from papers published this year and feature all kinds of systems and visual styles – here they are for posterity! Let us know your favourite in the comments Whole-embryo developmental imaging of zebrafish spinal cord neurogenesis From[…]

A domino effect on brain developmental evolution

Posted by on December 6th, 2019

The discipline “Evo-devo” studies the developmental basis of morphological evolution. In the field, some original animal models are emerging as interesting model organisms, enriching the knowledge in the field more and more. In the DECA team (Développement et évolution du cerveau antérieur, in French) we use an Evo-devo approach to study the developmental mechanisms responsible[…]

November in preprints

Posted by on December 2nd, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.  This month we found preprints detailing extensive mouse and fly knockout resources, exploring bacterial influences on development, and investigating mechanics in vivo and in silico. They were hosted on bioRxiv and arXiv. Let us know if we missed anything. Use these links to get to the section you[…]

October in preprints

Posted by on November 5th, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.  This month features a series of preprints on stem cell mechanics and tools to help you make organoids, some nectins and some nestins, plenty of auxin in our plant section, and some phantom crustaceans and macabre French genomics in our ‘Why Not’ section. They were[…]

“My balance comes from instability” thought Herzog (Saul Bellow, Herzog)

Posted by on October 28th, 2019

A bit of background The dependence of a protein’s function on its structure is a well-known phenomenon. Back in 1970’s, it was suggested that most proteins would fold into one energetically stable or favorable conformational state in the cell determined by their primary amino acid sequence. This led to the notion of “one sequence to[…]

September in preprints

Posted by on October 2nd, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.  In recent preprint news, CSHL, which runs bioRxiv, launched Transparent Review in Preprints (TRiP), a new project enabling journals and peer review services to post peer reviews of submitted manuscripts. In linked news EMBO Press and ASAPbio launched  Review Commons, a platform that peer-reviews research manuscripts in[…]

The birth of vision

Posted by on September 9th, 2019

By decoding the genetic mechanisms that control the neurons of the visual system, researchers at UNIGE are unveiling the first steps in the construction of vision, paving the way for regenerative eye medicine. A Press Release from the University of Geneva.   How is the retina formed? And how do neurons differentiate to become individual[…]