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A domino effect on brain developmental evolution

Posted by on December 6th, 2019

The discipline “Evo-devo” studies the developmental basis of morphological evolution. In the field, some original animal models are emerging as interesting model organisms, enriching the knowledge in the field more and more. In the DECA team (Développement et évolution du cerveau antérieur, in French) we use an Evo-devo approach to study the developmental mechanisms responsible[…]

November in preprints

Posted by on December 2nd, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.  This month we found preprints detailing extensive mouse and fly knockout resources, exploring bacterial influences on development, and investigating mechanics in vivo and in silico. They were hosted on bioRxiv and arXiv. Let us know if we missed anything. Use these links to get to the section you[…]

October in preprints

Posted by on November 5th, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.  This month features a series of preprints on stem cell mechanics and tools to help you make organoids, some nectins and some nestins, plenty of auxin in our plant section, and some phantom crustaceans and macabre French genomics in our ‘Why Not’ section. They were[…]

“My balance comes from instability” thought Herzog (Saul Bellow, Herzog)

Posted by on October 28th, 2019

A bit of background The dependence of a protein’s function on its structure is a well-known phenomenon. Back in 1970’s, it was suggested that most proteins would fold into one energetically stable or favorable conformational state in the cell determined by their primary amino acid sequence. This led to the notion of “one sequence to[…]

September in preprints

Posted by on October 2nd, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.  In recent preprint news, CSHL, which runs bioRxiv, launched Transparent Review in Preprints (TRiP), a new project enabling journals and peer review services to post peer reviews of submitted manuscripts. In linked news EMBO Press and ASAPbio launched  Review Commons, a platform that peer-reviews research manuscripts in[…]

The birth of vision

Posted by on September 9th, 2019

By decoding the genetic mechanisms that control the neurons of the visual system, researchers at UNIGE are unveiling the first steps in the construction of vision, paving the way for regenerative eye medicine. A Press Release from the University of Geneva.   How is the retina formed? And how do neurons differentiate to become individual[…]

August in preprints

Posted by on September 2nd, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.    The preprints were hosted on bioRxiv, PeerJ, and arXiv. Let us know if we missed anything, and use these links to get to the section you want:   Developmental biology | Patterning & signalling | Morphogenesis & mechanics | Genes & genomes | Stem cells, regeneration & disease modelling | Plant development[…]

July in preprints

Posted by on August 5th, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints. The preprints were hosted on bioRxiv, PeerJ, and arXiv. Let us know if we missed anything, and use these links to get to the section you want:   Developmental biology | Patterning & signalling | Morphogenesis & mechanics | Genes & genomes | Stem cells, regeneration & disease modelling | Plant development Evo-devo &[…]

June in preprints

Posted by on July 5th, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.  Another big haul this month covering everything from great ape cerebral organoids to collectively contracting choanoflagellates, the genes that control iris development to the signals and forces making boundaries in the hindbrain. The preprints were hosted on bioRxiv, PeerJ, and arXiv. Let us know if we missed anything, and[…]

Collaboration: All the things we cannot see (alone).

Posted by on June 3rd, 2019

By Miriam Rosenberg and Suparna Ray Most of what we know about axial patterning in insects comes from decades of careful, beautiful work done in flies. Thanks to the genetic screens of Christiane Nüsslein-Volhard and Eric Wieschaus in the late 1970’s, we learned that distinct classes of genes, many of them transcription factors, act in[…]