Much of what we understand about cellular metabolism has come from research by cancer biologists, who have known since the time of Otto Warburg that metabolic alterations go hand in hand with transformation. Building from this knowledge, in more recent years it has come into focus that many different tissues and cell types undergo metabolic changes that directly impact their function and differentiation. As such, correct metabolic re-wiring is beneficial and a requirement for appropriate cellular function, while aberrant metabolic reprogramming can lead to inappropriate function and have implications on a wide variety of disease states. In this meeting we aim to bring together researchers from different areas of biology, that may otherwise have little crossover, but for their common interest in how metabolism impacts cell differentiation and function.

Topics will span diverse areas such as cancer metabolism, organismal metabolism in disease, metabolic pathway engagement in cell function, metabolites as signaling molecules, mitochondrial biology, nutrient sensing, metabolism in tissue homeostasis and repair, neurometabolism, and metabolism in host-microbe interactions. This interdisciplinary meeting will bring together researchers working on immunity, metabolism, cancer, stem cells, neurobiology, and host-microbe interactions to gain a more integrated understanding of how metabolism impacts health and disease, with the aim of moving research in the field forward.

Key Sessions

• Mitochondria
• Metabolism and Host/Microbe Interactions
• Stem Cell Metabolism
• Neurometabolism
• Nutrient Sensing
• Cancer Metabolism
• Metabolism in Tissue Homeostasis and Repair
• Metabolites as Signaling Molecules
• Cell Metabolism in Disease and Inflammation

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