From Gametes to Embryo: basic research and clinical applications

Sexual reproduction is essential for the propagation of species. It produces new living organisms by combining the genetic information of female and male gametes: oocytes and sperm. Their fusion forms an embryo, whose development is probably the most complex biological event that takes place in nature. However, despite decades of research, much remains to be done to understand where we come from, from gametogenesis, through fertilization, implantation and embryonic development. Recent developments in stem cell biology, mechanobiology, single cell studies, epigenetics, imaging and others have allowed discoveries that were previously inconceivable. This is a field where basic and clinical/translational research are heavily intertwined and cross-fertilize each other.

The conference will include invited talks (see Faculty) as well as short communications selected from abstracts and posters. It will be a hybrid event, in Paris and online.

Registration is free but compulsory, follow this link.

Preliminary program:

Maud Borensztein, Montpellier, France: X-chromosome dynamics during female mouse development

Deborah Bourc’his, Paris, France: Epigenetic control of life-long spermatogenesis

Takashi Hiiragi, Utrecht, Netherlands: Multicellular coordination in context

Kikuë Tachibana, Martinsried, Germany: Mechanisms of zygotic genome activation in mouse embryos

Magdalena Zernicka-Goetz, Cambridge, UK and Caltech, USA: Principles of Self-Organization of Mammalian Embryos

Thomas Fréour, Nantes, France: Place of artificial intelligence in the evaluation of human embryonic development

Patricia Fauque, Dijon, France: Influence of culture media on human embryonic transcriptome

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