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2 x PhD positions available in Mok Lab at University of East Anglia on developmental hematopoiesis

Posted by , on 8 November 2022

Location: University of East Anglia

Closing Date: 21 November 2022

I have 2 x fully funded 4-year PhD projects available in my new lab within the BioMedical Research Centre at the University of East Anglia funded by the NRP DTP starting Oct 2023 open to UK and international students.

The first project is “Better (methy)late than never: Deciphering the role of DNA methylation in blood cell development” where we will map the global methylome of developmental hematopoiesis and interrogate the precise role of DNMTs in blood cell development. 🔬 🧬 🩸https://biodtp.norwichresearchpark.ac.uk/projects/better-methylate-than-never-deciphering-the-role-of-dna-methylation-in-blood-cell-development/

The second project is “Open or closed: Investigating the transcriptome and epigenome of embryonic hematopoiesis at single cell resolution” where we will use single-cell multi-omic sequencing approaches to comprehensively investigate the gene regulatory networks, which includes key genes and cis-regulatory elements, in embryonic hematopoiesis. 💉🩸 🐥

https://biodtp.norwichresearchpark.ac.uk/projects/open-or-closed-investigating-the-transcriptome-and-epigenome-of-embryonic-hematopoiesis-at-single-cell-resolution/

 

Please do email me (g.mok@uea.ac.uk) if you are interested or share with colleagues and students who you might think would be interested! Prospective students will be joining a fun, inclusive and supportive lab that has a supervisory team consisting of Dr Iain Macaulay, Dr Wilfried Haerty (both at the Earlham Institute), Prof David Monk and Prof Andrea Munsterberg (both at University of East Anglia). Deadline for applications is 21st Nov 2022.

 

There are other fantastic cell, molecular and developmental biology PhD projects also available at UEA funded by the NRP DTP which include:

David Monk – Allele-specific enhancer usage and genomic imprinting: a job for NOMe-seq

Andrea Munsterberg – Building the vertebrate spine: the neck to thorax transition.

Grant Wheeler – Using ATAC-seq to study placodal development in Xenopus

Sam Fountain – Allosteric modulation of P2X receptors: a molecular and in-silico approach to understand how drug-like ligands work

Rebecca Taylor – Investigating the activation of IRE-1 as a novel regulator of ageing

 

Start date: 1 October 2023

Closing Date: 21 November 2022

Scientific fields: Cell fate control and differentiation, Cardiovascular development, Cell biology, Chromatin and epigenetics, Early embryogenesis, Gene regulation

Model systems: Chick

Duration: Fixed term

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