ERC-Funded PostDoc in gene regulation in Montpellier

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Project:

Coordination between transcription and translation dynamics

In eukaryotes, the classical view of the central dogma assumes that transcription and translation are unconnected processes. However, many observations challenge this view and suggest that transcription as well as accompanying co-transcriptional events leave an imprint on the subsequent fate of the produced mRNA.

The overall goal of this project is to determine the impact nuclear co-transcriptional events on the fine-tuning of translation (in terms of levels, space, and time), and their functional benefits for precision of protein expression in a developing animal. The project leader will use genomics (RNA-seq, Ribo-seq), quantitative imaging and (opto)-genetic in Drosophila early embryos. More info here.

Qualifications

Prior experience with molecular biology, genomics, RNA biology or microscopy are essential.

Strong interest in developmental biology or mechanisms of gene regulation.

Drosophila genetic knowledge will be valuable but is not mandatory.

Ability to work as part of an international team is required.

A PhD in biology, biophysics or a closely related field is required by the start of the appointment.

Environment

IGMM, is located on the historic CNRS Montpellier “Route de Mende” campus. It is physically connected to CRBM and IRIM research institutes, forming a critical mass of 600 people who create an exceptional intellectual and technological dynamic environment. The labs at IGMM have access to high-tech facilities, in particular through BioCampus. This project will be performed in collaboration with Pr Jean-Yves Roignant (Univ Lausanne, Switzerland).