Junior researcher in Metabolism–Epigenetics Interactions During Embryonic Development

Open competition for a permanent position of junior researcher at INRAE, France:

The Research Unit Biology of Reproduction, Environment, Epigenetics, and Development (BREED), located in Jouy-en-Josas near Paris, France, conducts research on the various stages of embryonic and foetal development in mammals, with a focus on the short- and long-term impacts of environmental changes. Within this unit, you will join the Embryo, Gametes, Gonads (EGG) team, composed of 14 scientists and 13 technicians. The team’s research aims to understand the molecular, epigenetic and cellular mechanisms regulating foetal gonads differentiation, quality of gametes, and pre-implantation embryo development, as well as the influence of environmental factors on these processes.
Your research project will explore the interactions between energy metabolism and epigenetic modifications during embryonic development, in relation to the maternal environment. You will begin by investigating how metabolites present in the microenvironment of the bovine embryo affect chromatin remodelling and developmental competence. In a second phase, you will identify maternal environmental factors that influence the production of key metabolites involved in mitochondrial function and epigenetic regulation. The ultimate goal is to establish a link between maternal nutrition, early development, and adult reproductive health and fertility.

Applications are open up to March 5th