Post-doc position at the University of Nottingham-Stem cell biology/Developmental biology

Applications are invited for a Research Associate/Fellow to work on a BBSRC funded project to develop novel embryonic stem cell lines in the laboratory of Dr Masaki Kinoshita (Sutton Bonington Campus, University of Nottingham, UK).

In this project we seek to understand the molecular regulation of pluripotency of mammalian embryos (including mouse, human and livestock) and stem cells. We aim to develop novel chimaera competent embryonic stem cell lines from livestock embryos, characterise them using next generation sequencing based omics approach and perform comparable analyses with mouse and human systems. The differentiation potential of these cells will be assessed both in vitro and in vivo, therefore experience in manipulations of early mammalian embryos is a highly desirable requirement for the role. This position will be especially suited to candidates with interest in stem cell biology, chimaeric animal production and primordial germ cell differentiation. This post offers a unique opportunity to work in stem cell biology with farmed animals and to develop skills in state-of-the-art technologies.

Applicants must be highly motivated,self-driven and work independently, with a PhD in stem cell or developmental biology or related area of biological science (PhD students about to submit their thesis in a relevant area of stem cell biology will be considered). It is desirable that the successful candidate has considerable experience in some of the following areas: stem cell biology, developmental biology, transgenic animal and/or animal cloning technology, supported by a proven track record in scientific publications. Experience in bioinformatics is very relevant for the project. The successful candidate will play a key role in a highly collaborative research environment in this project, so a friendly and collegial attitude is crucial.