Post-doctoral research fellow in biology of pluripotency, lab of Austin Smith

You will lead a programme of investigations into the comparative biology of pluripotency and pluripotent stem cells in different mammals. A key goal will be to establish and validate naïve pluripotent stem cells from non-human primates and from livestock species using pluripotency network resetting and somatic cell reprogramming approaches. In addition, derivations from livestock embryos will be pursued in collaboration with Prof Ramiro Alberio, University of Nottingham.

The post will involve stem cell culture experimentation including molecular reprogramming, genetic manipulation, signalling pathway manipulation, and focussed chemical and genetic screening. Transcriptomic and multi’omics analyses will be carried out in partnership with computational/bioinformatics group members.