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Postdoc in Chromatin and Epigenetics

Posted by , on 17 December 2021

Job type: Postdoc

Location: Stockholm University, Sweden

Closing Date: 31 January 2022

We are pleased to announce a postdoc position in the laboratory of Professor Mattias Mannervik at the Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University.

The project will involve using genomic, genetic, and transgenic approaches in Drosophila to study the molecular mechanisms of transcriptional and chromatin regulator function during development. A combination of genomic methods such as Hi-C, scRNA-seq, PRO-seq, ChIP-seq and CUT&Tag are used to probe dorsal-ventral patterning of the embryo (Ing-Simmons et al. Nature Genet, 2021). A histone replacement system is used to examine the effects of amino acid substitutions in the histones on organismal development (Regadas et al. Mol Cell, 2021), and a modified CRISPR/Cas9 system is employed to target chromatin modifying enzymes to endogenous loci (Sujwan and Mannervik, Sci Rep, 2019). Read more about our work here:
Mannervik lab

The position is available immediately and requires a recent Ph.D. as well as extensive experience in molecular biology techniques. The successful applicant should have a high-quality publication record, and be passionate about studying gene regulation in development. The position will be funded with a fellowship, and includes health insurance.

Stockholm University is one of the largest and most prominent universities in Sweden, located in the nation’s capital city, beautifully surrounded by the first national city park in the world. For further information, see
Stockholm University
Relocation

Applications should comprise the following:
1) a personal statement describing your research interests (1-2 paragraphs), research experience (1–2 paragraphs) and why you apply for this position (1-2 paragraphs)
2) curriculum vitae
3) bibliography
4) names, e-mail adresses, and phone numbers of 2-3 references

Applications should be marked with reference number SU-465-0256-21 and submitted electronically as a single PDF file to mattias.mannervik@su.se and to jessika.lind@su.se

Salary: The position will be funded with a fellowship, and includes health insurance.

Closing Date: 31 January 2022

Scientific fields: Chromatin and epigenetics, Gene regulation, Early embryogenesis, Patterning

Model systems: Drosophila

Duration: Fixed term

Minimum qualifications: Recent PhD and experience with molecular biology techniques

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