Postdoctoral position in epigenetics of neural developmental and disorders

The Akizu lab seeks candidates for a postdoctoral position in epigenetic mechanisms of neural developmental and disorders. The applicant must have a recent PhD in relevant fields, research experience in epigenomic (i.e. ChIPseq, Cut&Run, ATACseq, Hi-C…) OR human pluripotent stem cell culturing and organoid differentiation methods, and at least one first author publication in an impactful scientific journal.

The ideal candidate must be highly motivated and creative with strong ability to design and carry out experiments with a high level of independence. The successful candidate will work full time in one of our recently funded projects while also collaborating with other lab members and investigators in our institution. As part of career development training the candidate will be encouraged to apply for fellowships, present posters and talks in scientifically relevant conferences, and contribute to manuscript writing and submission.

Our lab studies genetic and epigenetic mechanisms that perturb neuronal development, function or survival in neurodevelopmental and pediatric neurodegenerative diseases, with the ultimate goal to uncover therapeutic strategies. Our work begins when we identify the genetic causes of a disease. We then develop human pluripotent stem cell and animal models to study pathogenic mechanisms of the disease and to test therapeutic approaches. Experimental approaches that we use in our studies include the latest histology, cellular and molecular biology methods, and the most novel gene editing, metabolomic, proteomics and genomics approaches. Example publications include https://www.medrxiv.org/content/10.1101/2022.08.09.22278430v1.

The strategic location of our lab within the Children’s Hospital of Philadelphia and University of Pennsylvania Medical School offers an inspiring environment with multiple resources for career development in academia and industry among others.

We value diversity and seek talented and creative students without regard to gender identity, race, color, sex, sexual orientation, citizenship status, national or ethnic origin or any other background.

Interested individuals email your CV, a brief cover letter describing your scientific interests and contact information of two references to Naiara Akizu, at aquizun@chop.edu