Postdoctoral Positions in Brain Development

The mammalian cerebral cortex is unparalleled in cellular diversity and complexity. However, a requisite for proper cortical function is the neurogenesis of the appropriate ratio of cells and their correct localization within the cortex. The Simó lab is offering two NIH-funded post-doctoral positions to tackle these crucial events. Our lab is interested in understanding: 1) the role of microRNAs in cell fate determination during cortical development both in mouse and human models and 2) the molecular mechanisms by which ubiquitin-dependent degradation of defined signaling effectors regulate PN migration, localization, and layering in the cortex. To study these dynamic processes, we use mouse genetics, in utero electroporation, molecular techniques, proteomics, lipidomics, and multiple advanced imaging modalities including TIRF, confocal and state-of-the-art super-resolution technologies.

Successful candidates will enjoy a supportive, diverse, and stimulating laboratory environment with cutting-edge instrumentation and facilities, and a strong culture of training and mentorship.

Applicants must have a Ph.D., or MD degree and should have a demonstrated background in neuroscience, neurophysiology, and/or cell biology and signaling cascades. Previous experience in at least one of the following is recommended: enzymatic isolation of primary neurons, in utero electroporations, cell biology and cell signaling, calcium imaging, and fluorescence microscopy. The applicant should have a strong publication record, be able to independently design and conduct experiments, be an effective communicator and problem-solver willing to work within a collaborative team.

Successful applicants will be expected to stay abreast of current literature in the field, design and execute experiments, assist in the collection of data for grant applications, and to prepare their results for presentation at national and international scientific conferences and for publication in peer-reviewed journals. UC Davis is a supportive, diverse, and collaborative community, ideally situated in the sunny Sacramento Valley between beautiful Lake Tahoe and the San Francisco Bay Area.

TO APPLY:

Interested candidates should send their CV/biosketch, a cover letter expressing their interest in the position, and the name and email of three qualified references to Dr. Sergi Simó via email at ssimo@ucdavis.edu