Postdoctoral Research Associates (Bulstrode Lab – Cambridge Stem Cell Institute)

The Bulstrode Lab studies the biology of neural stem cells in development, cancer and neurodegeneration. We are also developing new technology for targeted delivery of treatments to the brain. Recent grant awards from Parkinson’s UK and Brain Research UK will each fund a Postdoctoral Research Associate to join the group and work respectively on:

(1) ‘Developing an Adaptable Dopamine Cell Therapy for Parkinson’s Using the HIF Pathway’

(2) ‘Gene and mRNA therapy approaches to Tumour Associated Macrophages in Glioblastoma’.

The successful candidates will have a strong basic science research track record at doctoral level. Experience in some or all of mammalian cell culture, routine molecular biology workflows, imaging, cloning, and next generation sequencing analysis is highly desirable.

We benefit from privileged access to human patient tissue resected at operation and to human embryo brain tissue, and you will be applying the above techniques to state-of-the-art human model systems including:

• Primary patient-derived cell lines
• Pluripotent stem-derived neurons and organoids.
• Human brain organotypic slice culture
• Isolated human brain cell fractions

Alongside the aptitude and initiative to pursue personal research objectives, candidates will need to demonstrate the scientific knowledge, expertise and enthusiasm to help guide students day-to-day, contribute scientifically and socially to the lab and wider institute, and contribute some admin and organisational duties. It is essential that the successful candidate can work both independently and as part of a research team, with good communication and organisational skills.

Further Details and application here: https://www.jobs.cam.ac.uk/job/47623/