Postdoctoral Scholar – Human Embryo Development & Reproductive Tissue Engineering

Are you passionate about making ground-breaking contributions to the field of human development and human reproduction? Join our lab at Stanford University, where you will play a critical role to drive scientific discoveries and advancing our understanding of the earliest stages of human embryo development. The annual salary starts from, dependent upon skills and previous experience. Initial appointment is 1 year with expected renewal after the first year for an additional 1-2 years. For more information, please contact Dr. Matteo Molè at mmole@stanford.edu , visit our website. The official opening can be found here.

Position Summary:We are seeking a highly motivated Postdoctoral Scholar to lead a multifaceted project focusing on investigating fundamental mechanisms of human embryo implantation. This is a unique opportunity to work at the intersection of developmental biology and tissue engineering, utilizing innovative technologies. Our research objectives are to elucidate the cellular behavior, invasion, and interactions between the embryo and maternal tissue, to employ single-cell technologies to profile the molecular crosstalk of the implantation niche and to employ gene editing to determine the genetic factors underlying successful implantation. By studying what goes wrong at the embryo-maternal interface, we aim to gain critical insights into the molecular causes underlying implantation failure and early pre-clinical miscarriages.

Key Responsibilities

• Lead your own project on cellular and genetic regulation of human embryo implantation.
• Establish collaborations with other members within the Department and wider Stanford community to establish new techniques and research directions.
• Apply and obtain competitive funding.
• Employ advanced imaging, spatial analysis, and sequencing-based technologies to dissect mechanisms of embryo development and gene regulation. Establishment of live imaging.

• Maintain meticulous research records and support operational/reporting responsibilities associated with clinical research.

Qualifications and Requirements

• PhD in developmental biology, genetics, cell and molecular biology, or a related field.

• Strong background and expertise in embryonic stem cell culture, organoids, and developmental biology. Expertise in mammalian cell culture is essential for this position, ideally with human embryonic stem cells. Familiarity with stem cell-derived embryo models would be desirable.

• Experience with advanced imaging techniques.
• Experience with single-cell transcriptomics.
• Familiarity with multi-omics techniques, spatial analysis including sequencing-based spatial technologies would be desirable.
• Familiarity with editing technologies, such as CRISPR/Cas9, would be desirable.

• Experience in carrying out independent and collaborative research. Proven experience with protocol development and research leadership. Excellent organizational skills and the ability to maintain meticulous records.

• Ability to plan and prioritize own work to meet deadlines, including using initiative to plan research programs. Working collaboratively with others and building working relationships with stakeholders at all levels. Demonstrates inclusivity and respect for all. Commitment to personal development and updating of knowledge and skills.

How to Apply

If you are passionate about exploring these topics and interested in working in a stimulating and collaborative research environment, we encourage you to apply. Please contact Matteo Molè at mmole@stanford.edu for anything related to the opening. To apply: submit your CV, 3 references letters, and a cover letter outlining your research interests and relevant experience. Join our vibrant and inclusive research community at the forefront of scientific innovation. We are part of the Department of Obstetrics and Gynecology at Stanford University and Dunlevie Maternal-Fetal Medicine Center for Discovery, Innovation and Clinical Impact. This is an exceptional opportunity to work in a cutting-edge research environment, drive transformative discoveries, and contribute to solving one of humanity’s greatest challenges.

Contacts

For enquires on projects and application process: Matteo Molè at mmole@stanford.edu, office phone: +1 (650) 7362 754. Further information on research can be found at https://med.stanford.edu/matteo-mole.html. Location: Stanford University School of Medicine: Division of Reproductive, Stem Cells and Perinatal Biology; Dunlevie Maternal Fetal Medicine Center for Discovery, Innovation and Impact.