the community site for and by developmental biologists

How to “Run” embryonic development

Posted by on July 24th, 2019

The term “embryonic development” was originally proposed some 2,400 years ago by Aristotle, however, many aspects of how the genome regulates development remain unclear. One major challenge of the modern Genomics Era is to better understand how transcriptional factors, transcriptional activators and repressors, regulate gene expression in order to support spatiotemporal outputs that change over[…]

the Node researcher database survey

Posted by on July 23rd, 2019

This survey is now closed. If you missed it but would still like to share your thoughts, just email The Node is planning to launch a database of developmental and stem cell biologists. The idea is to help people organising conferences, assembling committees and seeking speakers/referees to identify individuals that might not otherwise have[…]

Genetics Unzipped podcast: Cut. Paste. Pair. Repeat.

Posted by on July 19th, 2019

We’re exploring the dark heart of the genome, untying nature’s shoelaces, and looking back at the discovery of RNA splicing.

Development at the single cell level

Posted by on July 17th, 2019

Development recently published a bumper Special Issue devoted to single cell approaches to developmental biology. A multitude of model systems featured – from Dicty to Drosophila to mouse to zebrafish – and the issue’s Reviews, Spotlight and Hypothesis gave an overview of the field’s current challenges and opportunities.     The cover was chosen by[…]

Gene Regulatory Networks for Development Course – apply by 17 July

Posted by on July 11th, 2019

Applications are now open for this year’s Gene Regulatory Networks for Development at The Marine Biological Laboratory in Woods Hole, USA from October 13-26.  The application deadline is July 17th. The course is for graduate students, postdoctoral researchers, staff scientists and faculty members. It focuses on using experimental data and computational modeling to analyze gene regulatory networks controlling development.[…]

Funded early career places at Company of Biologists Workshop ‘Understanding Human Birth Defects in the Genomic Age’

Posted by on July 9th, 2019

The Company of Biologists Workshops provide leading experts and early-career researchers from a diverse range of scientific backgrounds with a stimulating environment for the cross-fertilisation of interdisciplinary ideas. In November, experts will gather in the beautiful surroundings of Wiston House in West Sussex with the aim of ‘Understanding Human Birth Defects in the Genomic Age‘. Organised[…]

The people behind the papers – Eduardo Leyva-Díaz and Oliver Hobert

Posted by on July 9th, 2019

This interview, the 66th in our series, was recently published in Development Transcriptional autoregulation occurs when transcription factors bind their own cis-regulatory sequences, ensuring their own continuous expression along with expression of other targets. During development, continued expression of identity-specifying transcription factors can be achieved by autoregulation, but until now formal evidence for a developmental requirement of autoregulation[…]

Genetics Unzipped podcast: Interview with Paul Nurse

Posted by on July 9th, 2019

In this episode we’re celebrating the Genetics Society’s centenary with past president and Nobel laureate, Sir Paul Nurse.

Fundraising for Suzanne Eaton search effort

Posted by on July 8th, 2019

Update: please read the latest statement from the MPI-CBG Our thoughts are with Suzanne’s family, friends and colleagues.       Suzanne Eaton, the molecular and developmental biologist based at the MPI-CBG in Dresden, is currently missing on the island of Crete (see the MPI’s statement and recent NBC news story for details). The search team[…]

June in preprints

Posted by on July 5th, 2019

Welcome to our monthly trawl for developmental biology (and related) preprints.  Another big haul this month covering everything from great ape cerebral organoids to collectively contracting choanoflagellates, the genes that control iris development to the signals and forces making boundaries in the hindbrain. The preprints were hosted on bioRxiv, PeerJ, and arXiv. Let us know if we missed anything, and[…]