the community site for and by developmental biologists

Pairing of segmentation clock genes results in robust pattern formation

Posted by on February 4th, 2021

By Oriana Q. H. Zinani, Kemal Keseroğlu, Ahmet Ay & Ertuğrul M. Özbudak: Gene expression is an inevitably stochastic process (Ozbudak et al., 2002). In contrast, embryonic development and homeostasis require cells to coordinate the spatiotemporal expression of large sets of genes. Many mechanisms are known to orchestrate this coordination, such as operons, bidirectional promoters,[…]

SciArt Profiles: Sydney Wyatt

Posted by on February 4th, 2021

In our third SciArt Profile we meet Sydney Wyatt, a PhD student based at the University of California, Davis.   Where are you originally from, where do you work now, and what do you work on? I am originally from a small Northern California town, Paradise. I went out of state to get my BS[…]

4D Morphological Atlas of C. elegans Embryogenesis

Posted by on February 2nd, 2021

A joint research team co-led by Prof. Chao Tang (Peking University, PKU), Prof. Zhongying Zhao (Hong Kong Baptist University, HKBU) and Prof. Hong Yan (City University of Hong Kong, CityU) has developed a novel computational tool that can reconstruct and visualize three-dimensional shapes and temporal changes of cells, speeding up the analytical process from thousands[…]

January in preprints

Posted by on February 2nd, 2021

Welcome to our monthly trawl for developmental biology (and related) preprints.  The preprints this month are hosted on bioRxiv, arXiv and, for the first time, (check out our new ‘Reviews’ section!) – use these links to get to the section you want. Developmental biology | Patterning & signalling | Morphogenesis & mechanics | Genes & genomes | Stem cells,[…]

Remembering Lewis Wolpert

Posted by on February 1st, 2021

On Friday we learned of the death of Lewis Wolpert, a huge figure in developmental biology, a popular science writer and communicator. Here we’ve gathered some memories of Wolpert from the internet – please share your own with a comment below the piece.     No one who met Lewis could fail to be impressed[…]

Genetics Unzipped podcast: 100 not out? Genes and ageing

Posted by on January 28th, 2021

We a look at the biological changes that underpin ageing, and how we can use this knowledge to live longer, healthier lives.

Development presents… preLights third birthday special

Posted by on January 26th, 2021

    The next webinar in our Development presents… series will be a little different: rather than being chaired by a Development editor, the preLights team will be in control. preLights is the preprint highlights service run by the biological community and supported by The Company of Biologists, and in February they celebrate their third[…]

A facial birth defect is caused by perturbation of extreme long-range enhancers

Posted by on January 25th, 2021

By Hannah Long  From the almost identical faces of monozygotic twins, we can appreciate that facial appearance is encoded for the most-part in the DNA of our genomes. Therefore, changes to this DNA sequence can contribute to the variation in facial appearance seen between humans, and at the more extreme end of the spectrum can[…]

SciArt Profiles: Justine Renno

Posted by on January 22nd, 2021

The second in our new series of SciArt profiles features Justine Renno, a Master’s student in Bordeaux.   Where are you originally from, where do you work now, and what do you work on? I am originally from Alsace in France. I got a Master’s in developmental biology which I ended with a 6 months[…]

Competition: searching for a new head(er)

Posted by on January 21st, 2021

We’ll soon be launching a newly designed Node homepage to help make our historical content easier to find and improve navigation through the various parts of the site. To accompany this change we’re going to refresh our header image – that’s the letterbox-shaped image you see above the menu bar. Currently we circulate between these[…]