the community site for and by developmental biologists

Catch Me if You Can: An elusive underpinning for Arx(GCG)10+7-mediated apoptosis in X-linked infantile spasms syndrome

Posted by on June 3rd, 2020

This post highlights the approach and finding of a new research article published by Disease Models and Mechanisms (DMM). This feature is written by Olivia Howell as apart of a seminar at The University of Alabama (taught by DMM Editorial Board member, Prof. Guy Caldwell) on current topics related to use of animal and cellular[…]

Stripe by stripe, zebrafish model provides transparent look into Fibrolamellar Carcinoma mechanism

Posted by on June 3rd, 2020

This post highlights the approach and finding of a new research article published by Disease Models and Mechanisms (DMM). This feature is written by Joseph I. Kaluzny as apart of a seminar at The University of Alabama (taught by DMM Editorial Board member, Prof. Guy Caldwell) on current topics related to use of animal and[…]

Virtual EWM2020 22nd-23rd June

Posted by on June 2nd, 2020

EWM2020 meeting is going online June 22nd-23rd. follow by a Poster Session June 29-30th with new abstract submission Details  at shorturl.at/mvFY7 & Twitter Ewbank Pujol lab  #EWM2020;  Wormbase     (+1 rating, 1 votes)Loading…

How I defended my Ph.D. from a remote location in India amidst COVID-19 lockdown?

Posted by on June 2nd, 2020

Author: Suvimal Kumar Sindhu, Graduate Student @ Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, 208016, India Email: suvimal.sindhu@gmail.com   Having joined my Ph.D. programme at India Institute of Technology Kanpur in India, I always witnessed my senior colleagues defending their Ph.D. thesis with panache and grace; for juniors like me such visuals were highly captivating[…]

May in preprints

Posted by on June 1st, 2020

Welcome to our monthly trawl for developmental biology (and related) preprints.    A real monster of a month, May, with masses of preprints uploaded by scientists in various stages of lockdown. Let us know if we missed anything and use these links to get to the section you want:   Developmental biology | Patterning & signalling[…]

Research Highlight #4: Macrophages in human development

Posted by on June 1st, 2020

Today we return our interest to human development, focusing on a special blood cell: the macrophage. Produced in multiple, stem cell-independent waves, macrophages colonize the developing foetus early on, forming several tissue-resident populations. This includes the microglia which are essential for brain and spinal cord development. In this paper, the authors looked into macrophage development[…]

Bioinformatics challenges in multidisciplinary research

Posted by on May 27th, 2020

Currently, bioinformatics is playing an increasingly important role in life science research. Biologists, clinicians and biomedical researchers have become more dependent on bioinformatics outcomes. Despite the crucial role of bioinformatics in accomplishing multidisciplinary projects, collaborations between biologists and bioinformaticians encounter several difficulties. Here, I outline different types of collaborations and provide an overview of how[…]

The people behind the papers – Charles Sheehan, John McMahon and Debby Silver

Posted by on May 27th, 2020

This interview, the 76th in our series, was published in Development earlier this year.  Interneurons are crucial to cortical function and their dysregulation has been implicated in various neurological pathologies, yet how they are generated during development is still poorly understood. A new paper in Development investigates interneuron neurogenesis in the mouse embryo and its[…]

Research Highlight #3: IL-1 regulates haematopoietic stem cell pool size via PU.1

Posted by on May 25th, 2020

Today, we move to mouse adult haematopoiesis, with an elegant work on inflammation and stem cell biology. As always, feedback is more than welcome! Chronic inflammation is one of the classic events underlying aging and infection response. When associated with loss of quiescence in haematopoietic stem cells (HSCs), it is commonly the initiating event in[…]

Staying connected during the COVID19 pandemic

Posted by on May 21st, 2020

Among many other (many more important) things, pandemic times have meant an end to travel, which for the Development team means no conferences and no lab visits. For me personally, it’s meant cancelled trips to Shanghai, Kyoto, Washington and Chicago, and while I’m delighted to be keeping my carbon footprint down, I’m definitely missing the[…]