PhD Studentship – Discovering Novel Brain Tumour Initiation Mechanisms

REF: PUPSMD-04-INT-15-16

Start date: October 2016

A 3-year PhD studentship is available in the group of Dr. Claudia Barros, Peninsula School of Medicine, Plymouth University, UK. The project will examine the role of novel candidates genes in brain tumour initiation and growth, following a single-cell transcriptome screen performed in the laboratory. Drosophila will be used to test candidate genes in the conversion of normal neural stem lineage cells into brain tumour initiation cells, via genetic gain and loss of function assays. Translation of findings into human-based systems will be performed by assessing human gene orthologues in glioma samples and patient-derived glioblastoma stem cell lines.

We are looking for a highly motivated graduate with a degree in biomedical Sciences or related field (1^st class or 2:1 equivalent), and preferably with a relevant Masters qualification. International students must also have an IELTS score of 7.0 or above (or equivalent qualification). Experience in genetics, molecular biology, immunohistochemistry, cell culture, protein work and/or imaging is desired. A high interest in neural stem cells and brain tumour biology is essential.

For enquires regarding the project, please contact Dr. Claudia Barros (claudia.barros@plymouth.ac.uk).

To apply:

Follow the link: https://www.plymouth.ac.uk/study/postgraduate and click ‘Apply’ to access the application form. Please mark the application for the attention of Bernice Wilmshurst and indicate the project Reference. Please Note: you do not need to submit a project proposal with your application.

Funding notes: The stipend will be £14,057 (based on full time 2015/16 rate). Tuition fees will be paid at the home/EU rate. Candidates who are not eligible for Home/EU fees will be liable for the difference between ‘home student fees’ and ‘international student fees’. For the 15/16 academic year the difference in fee is £10,800. If you are selected you will be required to provide financial assurances.

Closing date for applications: Noon 21^st March 2016. Shortlisted candidates will be invited for interview. We regret that we may not be able to respond to all applications. Applicants that have not been contacted by 11^th May 2016 should consider their application unsuccessful on this occasion.

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