Post-doctoral fellowship in Cologne, Germany

The Center for Molecular Medicine Cologne (CMMC) is a multidisciplinary center at the University of Cologne providing a forum that brings together physician scientists with basic researchers from the Faculty of Medicine and the Faculty of Mathematics and Natural Sciences to perform competitive basic, disease-oriented research. The mission of the CMMC is to advance the understanding of the underlying molecular and cellular mechanisms as a prelude to improving prevention, diagnosis and treatment of many common health problems. For further information, please visit http://www.zmmk.uni-koeln.de.

The Center for Molecular Medicine Cologne invites applications of bright and motivated individuals for the Junior Research Group “Developmental Genomics” of Dr. Alvaro Rada-Iglesias.

One full time Post-doctoral fellow

The position is immediately available for 24 months with the possibility of extension. The position is based on the German TV-L salary conditions. The CMMC places strong emphasis on gender equality and seeks to increase the proportional representation of women in this field. Applications from female scientists are especially welcomed; suitably qualified women will be given preferential consideration unless other candidates clearly demonstrate superior qualifications. We also welcome applications from disabled candidates, who will also be given preferential consideration over applicants with comparable qualifications.

What we look for:
The ideal candidate should hold a PhD and demonstrated research experience in developmental biology, preferentially in one or more of the common vertebrate model organisms (mouse, chicken, frog or zebrafish). Experience with routine molecular biology techniques is also required. In addition, candidates with previous experience in stem cell or chromatin biology are also encouraged to apply. We look for highly motivated candidates willing to expand their previous expertise and interests as part of a multidisciplinary and collaborative scientific environment. The successful candidate will receive mentoring and will be given the opportunity to develop his/her own projects in preparation for a future independent career.

Research overview:
During mammalian embryogenesis, cell fates are acquired according to highly defined spatiotemporal patterns, which involves the deployment of cell type specific gene expression patterns as developmental programs unroll. Focusing on the crosstalk between transcription factors and epigenetics, our group aims to better understand the transcriptional regulatory principles that orchestrate the earliest steps of mammalian development. In doing so, our ultimate goal is to characterize the vast non-coding genomic space of the human genome and to investigate how genetic variation within non-coding regulatory elements can contribute to common and congenital human diseases.

In order to gain a global as well as mechanistic understanding of these biological processes, our lab uses a multidisciplinary approach where in vitro (i.e. human and mouse embryonic stem cells) and in vivo developmental models are combined with biochemical and genomic approaches. Please visit http://zmmk-ari.uni-koeln.de/Home.html to learn more about our previous work and interests.

Research environment:
CMMC along with its partner institutes such as the Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases, Cologne Center for Genomics and Max Planck Institute for Biology of Ageing research all located in a same campus provides a vibrant scientific community. Therefore, the CMMC`s JRG in “Developmental Genomics” is placed perfectly at an environment where the basic research meets its cutting edge of translational science.

If you have further questions please do not hesitate to contact Dr. Alvaro Rada-Iglesias: aradaigl@uni-koeln.de

Please forward your complete application including CV, a brief statement of scientific interests and three reference letters (in a single pdf document) until 31.05.2013 by e-mail, quoting the reference number e129 to Dr. Alvaro Rada-Iglesias: aradaigl@uni-koeln.de and in CC. to Dr. Debora Grosskopf-Kroiher (Managing Director, Center for Molecular Medicine Cologne) (zmmk-office@uni-koeln.de).

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