A postdoctoral position to study role of Par-3 in E-cadherin recycling and signalling

A postdoctoral BBSRC funded position is available to study role of Par-3 in E-cadherin recycling and signalling in the group led by Dr Natalia Bulgakova http://www.sheffield.ac.uk/bms/research/bulgakova

The focus of the Bulgakova group is on discovering roles and regulation of cell-cell adhesion using Drosophila as a model organism. We have recently discovered that the protein Par-3 maintains the key cell-cell adhesion protein E-cadherin within the recycling route. The successful applicant will study the mechanism of this Par-3 function and its role in the development and physiology of the animal. The project will employ a combination of molecular genetics, live imaging, and protein biochemistry.

The successful applicant will have a PhD or equivalent experience relevant to studying cell-cell adhesion or intracellular trafficking, knowledge of working with genetic model systems and be highly motivated. Experience in using Drosophila, molecular biology, protein biochemistry, and confocal microscopy, and knowledge of cell-cell adhesion, cell polarity and intracellular trafficking will be an advantage. The successful candidate will be expected to have excellent interpersonal and communication skills, be highly independent, and committed to research in a fast-moving and competitive field.

Fixed-term with an immediate start date and an end date of 31 March 2020

For more information and to apply, please see http://www.jobs.ac.uk/job/BBL246/research-associate/

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