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Displaying posts with the tag: is_archive

Embryonic hydraulics triumphs

Posted by , on 26 June 2019

In this article I share with you a more personal, chronological account of how our story unfolds (recently published in Nature), and highlight some key events and insights that help ...

Beyond morphogen signaling

Posted by , on 25 June 2019

By Dörthe Jülich & Scott Holley   Organizers pattern surrounding tissues via secreted morphogens that specify different cell states as a function of concentration. Wolpert’s French Flag model is commonly ...

Decoding light for developmental timing

Posted by , on 13 June 2019

Shruti Vemaraju¹ and Richard A. Lang¹-²  ¹Center for Chronobiology,¹The Visual Systems Group, Abrahamson Pediatric Eye Institute, Division of Pediatric Ophthalmology, ²Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH ...

Collaboration: All the things we cannot see (alone).

Posted by , on 3 June 2019

By Miriam Rosenberg and Suparna Ray Most of what we know about axial patterning in insects comes from decades of careful, beautiful work done in flies. Thanks to the genetic ...

Notch awakens: transitioning to the first differentiation step

Posted by , on 3 May 2019

The story behind our recent paper in eLife.   In the mid-1900s, Conrad Hal Waddington introduced the idea of development as a series of branching decisions taken under the control ...

Forces maintain order between cells

Posted by , on 30 April 2019

Written by Antoine Fruleux and Arezki Boudaoud As Lewis Wolpert put it (Wolpert, PLoS Biology 2010), if you extend your two arms, you will likely find that they match in ...

Hot fish and the energetics of early development

Posted by , on 10 April 2019

The story behind our recent paper “Heat Oscillations Driven by the Embryonic Cell Cycle Reveal the Energetic Costs of Signaling” Developmental Cell, 48(5), pp.646–658.e6. At the end of 2014, a ...

The pattern of research

Posted by , on 2 April 2019

The correct patterning of embryonic tissues is essential for normal development. Aberrant patterning can lead to developmental abnormalities and pathogenic defects. Therefore, studying developmental patterning is important to better understand ...

Making Multiciliated Cells: The Guardians of Our Airways

Posted by , on 1 April 2019

With air pollution on the rise, our respiratory system is continually abused by a barrage of harmful substances that we breathe in with each inhalation. Fortunately, we are equipped with ...

Plant stem cells strive towards equality

Posted by , on 8 February 2019

By George Bassel and Iain Johnston Multicellular organs consist of collections of cells which come together to achieve what individual cells cannot. The establishment of order in complex tissues has ...

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