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Avian insights into human ciliopathies

Posted by on February 22nd, 2021

Press release for a recent Development paper from Samantha Brugmann’s lab Ciliopathies are genetic disorders caused by defects in the structure and function of cilia, microtubule-based organelles present on the surface of almost every cell in the human body which play crucial roles in cell signalling. Ciliopathies present a wide range of often severe clinical[…]

Development presents… November webinar

Posted by on November 11th, 2020

Talks now available here!     The second webinar in the Development presents… series coincides with the November release of our Special Issue: The Origins and Mechanisms of Developmental Disorders. The Special Issue showcases the role of developmental biologists in addressing developmental disorders – the leading biological cause of death for children of all ages[…]

Zipping up the neural tube

Posted by on April 21st, 2020

Matteo A. Molè & Andrew J. Copp Molè et al., Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure. Dev. Cell. 52, 321-334.e6 (2020). Zippering is a striking phenomenon whereby two opposing epithelial tissues become progressively united in one direction over a period of time. Similar, to the travel of a zip fastener,[…]