Posted by AlessandroDonada on June 1st, 2020
Today we return our interest to human development, focusing on a special blood cell: the macrophage. Produced in multiple, stem cell-independent waves, macrophages colonize the developing foetus early on, forming several tissue-resident populations. This includes the microglia which are essential for brain and spinal cord development. In this paper, the authors looked into macrophage development[…]
Posted by AlessandroDonada on May 18th, 2020
Hi there! Today’s highlight is focusing on a major question for the haematology community: what is causing blood stem cell heterogeneity? Please do not hesitate to let me know your thoughts in the comments here or on Twitter (@BioRugby)! Highlight #2: Chromatin accessibility is the main source of heterogeneity in foetal haematopoiesis We have[…]
Posted by The Francis Crick Institute on September 20th, 2017
OVERVIEW We are seeking a highly motivated and collaborative Laboratory Research Scientist in the area of human embryology and stem cell biology to join Dr. Kathy Niakan’s laboratory. The lab has identified several signalling pathways that may be operational in the human embryo to regulate the establishment or maintenance of pluripotent epiblast progenitor cells[…]