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Growing a body, one tiny tug at a time

Posted by on February 24th, 2020

From Knowable Magazine’s Special Report: Building Bodies. For an introduction to the series see Eva Emerson and Rosie Mestel’s Node post. For decades, genetics and biochemistry have formed the bedrock of developmental biology. But it turns out that physical forces — the way cells push, pull and squeeze each other — play a huge role,[…]

BSDB Gurdon/The Company of Biologists 2019 Summer Studentship Report – Jake Cornwall Scoones

Posted by on January 29th, 2020

Established by the British Society for Developmental Biology in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the feedback[…]

Beyond morphogen signaling

Posted by on June 25th, 2019

By Dörthe Jülich & Scott Holley   Organizers pattern surrounding tissues via secreted morphogens that specify different cell states as a function of concentration. Wolpert’s French Flag model is commonly used to describe how morphogen gradients specify different fates. Our recent study integrates tail organizer signaling with control of morphogenesis during vertebrate body elongation (Das,[…]

The people behind the papers – Joe Shawky & Lance Davidson

Posted by on October 24th, 2018

The construction of complex three-dimensional tissue structures during embryogenesis requires precise control of cell and tissue mechanics. The Xenopus embryo provides a powerful tool for interrogating this relationship, as demonstrated by a recent Development paper reporting the use of tissue explants to test predictions of mechanical models. We caught up with first author and recent graduate Joseph[…]

On Growth and Form at 100: Perspectives from the field

Posted by on November 28th, 2017

What explains the lasting legacy of D’Arcy Thompson’s ‘On Growth and Form’? A century on from the publication of the first issue, we reached out to authors from Development’s special issue celebrating the centenary and asked what the book meant to them.     Arkhat Abzhanov Natural History Museum (London) & Imperial College London “There are[…]

On Growth and Form at 100: An interview with Matthew Jarron

Posted by on November 28th, 2017

In late September I boarded a tiny propeller plane to Dundee to meet Matthew Jarron, who curates the University of Dundee’s D’Arcy Thompson Zoology Museum. We had seen Matthew speak about On Growth and Form at a Royal Society event over the summer, and realised he would be a perfect person to interview to give[…]

On Growth and Form at 100: Morphogenesis one century after On Growth and Form

Posted by on November 28th, 2017

This editorial by Thomas Lecuit and  L. Mahadevan originally appeared in Development’s Special Issue: On Growth and Form – 100 Years On     Morphogenesis, the study of how forms arise in biology, has attracted scientists for aeons. A century ago, D’Arcy Wentworth Thompson crystallized this question in his opus On Growth and Formusing a series[…]

The people behind the papers: Thanh Vuong-Brender & Michel Labouesse

Posted by on March 30th, 2017

This year marks the centenary of D’Arcy Thompson’s On Growth and Form, an attempt to outline the physical and mathematical principles underpinning the generation of biological form. Modern day developmental biologists, bolstered by new technologies, have taken up Thompson’s cause to try to understand the mechanics of development, particularly with regard to morphogenesis. While the generation[…]

Carthew & Mani Labs Postdoc Search

Posted by on May 20th, 2016

The Carthew and Mani Labs are looking to hire a joint postdoc with familiarity in live-imaging and quantitative analysis. Building on the expertise of both labs, the goal of the project is to construct a live imaging platform for eye development with a view to explore the coupled dynamics of cell-cell signaling, mechanical forces, and[…]

@ICAR 2012: Introductory Workshop on the Mechanics of Plant Growth

Posted by on June 26th, 2012

Please join us on the first day of ICAR 2012  (Tuesday 2nd July 16.00-17.30) for a series of short topical introductions to the field and discussions. Find out how mechanics could enrich your everyday view of plants, and your research! The mechanics of plant growth is a historically rich field, which has provided great insight[…]