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Postdoctoral Position in Signaling Mechanisms

Posted by on October 25th, 2016

Postdoctoral Position open at: Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California   An NIH-funded postdoctoral position is available to investigate the signaling functions of retinoic acid (RA) during mouse embryo development. Our laboratory has reviewed recent advances in this field: Cunningham, T.J. and Duester, G. Mechanisms of retinoic acid signalling and its roles[…]

Retinoic Acid Gradient Directly Visualized During Zebrafish Gastrulation

Posted by on April 11th, 2013

Retinoic acid is one of the most important signaling molecules during development, and that the embryo gets the right levels of this small molecule is critical. Too much or too little, and the basic patterning of the nervous system and many other organs goes terribly wrong. Indeed, you have to think for a bit to[…]

In Development this week (Vol. 139, Issue 18)

Posted by on August 21st, 2012

Here are the highlights from the current issue of Development:   Retinoic acid’s developmental role illuminated The role of all-trans retinoic acid (RA) in hindbrain development and other developmental processes is usually studied by blocking endogenous RA synthesis and then continuously supplying exogenous RA by soaking embryos in all-trans RA or by implanting RA-soaked beads.[…]

In Development this week (Vol. 138, Issue 4)

Posted by on January 26th, 2011

Here are the research highlights from the current issue of Development: New moves in haematopoiesis: rumba and samba Vertebrate haematopoiesis relies on a pool of haemetopoietic stem/progenitor cells (HSPCs) that can self-renew and differentiate into all haematopoietic lineages. But what are the molecular mechanisms that regulate this process? Here, Zilong Wen and co-workers (p. 619)[…]