the community site for and by developmental biologists

Postdoctoral fellowship in Applied Developmental Immunology

Posted by on June 22nd, 2018

The Maehr lab (http://maehrlab.net/) is looking for a team member in the area of developmental immunology and human pluripotent stem cell-based disease models. Envisioned projects will utilize pluripotent stem cell differentiation approaches, together with assays of thymus and T cell development, to decipher the molecular underpinnings of human immune syndromes such as thymus dysfunction-based autoimmunity[…]

Unraveling tissue interactions coordinating neuromuscular morphogenesis: a journey through serendipity

Posted by on June 20th, 2018

An emerging trend in developmental biology focuses on the role of cell adhesion in modulating tissue morphogenesis. Spectacular advances have shed light on how modulation of adhesion between equivalent cells orchestrates the acquisition of forms. However, how interactions at complex interfaces between distinct neighboring cell types influence tissue growth remains to be elucidated. In a[…]

Lighting Up the Central Dogma in Development

Posted by on June 19th, 2018

We recently published a manuscript in Cell that describes a method to image transcription factor concentration dynamics in real time, in living embryos, using a nanobody-based protein tag that we call the “LlamaTag.” We were particularly excited about these investigations because this new technology overcomes a major technical obstacle to understanding how gene-expression dynamics are[…]

Gene Regulatory Networks for Development

Posted by on June 19th, 2018

Applications are now open for this year’s Gene Regulatory Networks for Development which will be at The Marine Biological Laboratory in Woods Hole, USA from October 14- 27.  The application deadline is July 20.  The course is for graduate students, postdoctoral researchers, and faculty members and it focuses on using experimental data and computational modeling to analyze gene regulatory[…]

Research Assistant at Genetics, University of Cambridge (Germline Development)

Posted by on June 19th, 2018

The Karam Teixeira lab (https://karamteixeira.wixsite.com/website) at the University of Cambridge (Department of Genetics) is looking to recruit a Research Assistant to support a range of projects being carried out in our research group. We are primarily interested in germline development (stem cell regulation and genome defense mechanisms) and we use the Drosophila ovary as a model system[…]

Post-doctoral position at Cincinnati Children’s Hospital Medical Center

Posted by on June 18th, 2018

Post-doctoral positions are available in Dr. Samantha Brugmann’s lab to study vertebrate craniofacial development and disease, with an emphasis on the role of the primary cilium in these processes. For information about specific research areas see http://www.cincinnatichildrens.org/research/divisions/p/plastic/labs/brugmann/default/.   Qualifications: Applicants should possess a Ph.D. in a relevant field, such as Biology, Biochemistry, Genetics or another[…]

PhD in nerve/tumor interactions and nervous system development

Posted by on June 18th, 2018

Applications are invited from highly motivated individuals dedicated to peruse a PhD and who are interested in nerve/tumour interactions and nervous system development.    PROJECT DESCRIPTION During tumour progression nerves and tumours interact resulting in tumour cells using nerves as a metastatic route out of the organ, through a process called perineural invasion (PNI). While this[…]

New embryo phenotype data from the DMDD programme

Posted by on June 15th, 2018

Following our latest data release, the DMDD website (dmdd.org.uk) now contains detailed phenotype data for nearly 700 embryos from 82 different knockout mouse lines. Highlights include the identification of limb defects and cysts in Col4a2 knockouts and replication of the major features of Meckel syndrome in B9d2 knockouts. We have begun to add immunohistochemistry image[…]

Call for papers: Development at the single cell level

Posted by on June 14th, 2018

Development is pleased to welcome submissions for an upcoming special issue on ‘Development at the single cell level’. This special issue aims to showcase the best research in stem cell and developmental biology, building on the rapidly evolving tools of single cell analysis. The issue will be guest-edited by Allon Klein and Barbara Treutlein, working alongside our team of[…]

Polarizing morphogenesis: epithelia dance the polonaise

Posted by on June 13th, 2018

The story behind our recent paper: Counter-rotational cell flows drive morphological and cell fate asymmetries in mammalian hair follicles. Maureen Cetera, Liliya Leybova, Bradley Joyce & Danelle Devenport, Nature Cell Biology.    Planar cell polarity (PCP) is a fascinating biological problem because it spans such vast biological scales, from nanometers to meters of spatial organization. When[…]

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