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Preprints promote transparency and communication

Posted by on August 12th, 2018

Carmen Adriaens1, Gautam Dey2, Amanda Haage3, Wouter Masselink4 *, Sundar Ram Naganathan5, Lauren Neves6, Teresa Rayon7, Samantha Seah8, Srivats Venkataramanan9.   1. Center for Cancer Biology, VIB, KU Leuven, Leuven, Belgium & Center for Cancer Research, NCI/NIH, Bethesda, MD, USA 2. MRC Lab for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK 3. Department[…]

Stem cell makes its own niche: the story behind the paper

Posted by on July 7th, 2018

In our recent paper published in Nature, we unravel a new mechanism of an extracellular matrix protein secreted by muscle satellite (stem) cells, thereby playing the unusual role of acting as a signaling molecule to maintain the stem cell population. Here, I share the story behind this discovery and discuss the questions related to niche[…]

Towards understanding the quirks of human brain evolution

Posted by on June 28th, 2018

In early June, a group of 30 world-leading experts came together thanks to an invitation by the Company of Biologists to Wiston House (Sussex, UK) to discuss our current understanding about evolutionary and molecular mechanisms that contributed to developing the specific qualities of our human brains. Fortunately, the Company of Biologists offers fully funded participation[…]

Redefining the Aging Process

Posted by on May 4th, 2018

This post highlights the approach and findings of a new research article published in Disease Models and Mechanisms (DMM). This feature was written by J. Brucker Nourse Jr. as part of a graduate level seminar at The University of Alabama (taught by DMM Editorial Board member, Prof. Guy Caldwell) on current topics related to use[…]

YEN Conference 2018: Abstract submission and registration is open!

Posted by on April 11th, 2018

***Abstract Deadline is Saturday, 14th April!*** Young Embryologist Network Conference 2018 14th May 2018 The Francis Crick Institute, London, UK   This year we are pleased to announce Professor Wolf Reik as our keynote speaker. His research group, based at the Babraham Institute, investigates the roles of epigenetic gene regulation in mammalian development. We are also honoured to[…]

When the obvious fails, look at the unexpected: interneuron individual behavior affects the population migration.

Posted by on March 19th, 2018

The story behind our paper: Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. Carla G. Silva, Elise Peyre, Mohit H. Adhikari, Sylvia Tielens, Sebastian Tanco, Petra Van Damme, Lorenza Magno, Nathalie Krusy, Gulistan Agirman, Maria M. Magiera, Nicoletta Kessaris, Brigitte Malgrange, Annie Andrieux, Carsten Janke, Laurent Nguyen   The research behind this article is a[…]

Why more is better in comparative developmental biology…

Posted by on January 26th, 2018

Our recent paper in “Nature” [1] deconstructs molecular arguments that have been used to homologize bilaterian nerve cords. Our work illustrates well the strength of the comparative approach and the broad sampling across the animal tree of life that we use in my research group at the Sars Centre for Marine Molecular Biology.   Evo-Devo[…]

Explaining Developmental Biology to non-specialists

Posted by on January 24th, 2018

The BSDB recently initiated an advocacy campaign, starting with (1) the gradual development of the best arguments that can be used as elevator pitches in discussions, presentations, applications or publications, and (2) the collation of support resources which were first published on the BSDB website and are now present in improved version on The Node.[…]

Matthew Cobb: What makes great biology?

Posted by on January 19th, 2018

Prof. Matthew Cobb (The University of Manchester) Plenary talk given at the School of Biological Sciences symposium on Friday, 12 January 2018 Matthew Cobb is an inspiring advocate and communicator of science, in particular of biology. This is clearly reflected in his books and articles about the history of biology (and beyond), and his various[…]

Developmental biology: ‘not a confined, specified discipline’?

Posted by on January 10th, 2018

Catching up after the holidays, I finally got around to reading Scott Gilbert‘s recently published essay in PloS Biology. In case you haven’t seen it yet, the essay proposes that developmental biology is ‘the stem cell of biological disciplines’, and that many other areas of biology – such as cell biology, genetics, immunology, oncology and[…]