Marchantia square

A day in the life of a Marchantia lab

J Knoblich square

An interview with Juergen Knoblich

brain sex differences squared

Adventures in Studying Brain Sex Differences

lung organoids

Three dimensional human lung tissue in a dish

Question of the month- lab size

Posted by on May 28th, 2015

Lab sizes vary considerably, from small groups that include only the lab head and maybe a student or postdoc, to huge enterprises of several dozen people, including senior postdocs that manage smaller sub-groups under the overall supervision of the PI. What are the advantages of small versus large labs? Is it inevitable that a lab must continuously increase in size to […]
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Mole’s Wow! So now you have your own lab! Part III- The pact

Posted by on May 22nd, 2015

This cartoon was first published in the Journal of Cell Science. Read other articles and cartoons of Mole & Friends here.   To read part I- ‘The imposter’ click here. To read part II- ‘The teaching monster’ click here.
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Animal models for studying neural crest development: is the mouse different?

Posted by on April 28th, 2015

In the latest issue of Development, Elias Barriga, Paul Trainor, Marianne Bronner and Roberto Mayor have contributed a Spotlight article that discusses conserved and non-conserved aspects of neural crest development across vertebrates, and highlights potential concerns or caveats regarding the use of the mouse for the analysis of early neural crest development. The piece raises a number […]
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A response to NIH-RFI on funding policies and sustainability of biomedical research

Posted by on April 24th, 2015

Currently NIH has put out a request for information (RFI) to solicit input from the scientific community regarding “Optimizing Funding Policies and Other Strategies to Improve the Impact and Sustainability of Biomedical Research”(NOT-OD-15-084). The deadline to submit a response is May 17th 2015. More information can be found at Rock Talk blog post. Response need […]
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Question of the month- CRISPR technology

Posted by on April 23rd, 2015

This week a group in China published a paper in Protein & Cell claiming to have genetically edited a human embryo using CRISPR technology. This paper is generating a lot of debate for many reasons, from the type of embryo used in the experiment, to where it was (or wasn’t) published. More broadly though, it forces us to think about […]
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”The revolution is not an apple that falls when it is ripe. You have to make it fall.” – The Nurse review of science funding.

Posted by on April 10th, 2015

The following is my response to the Nurse review on scientific funding call for evidence: https://www.gov.uk/government/consultations/nurse-review-of-research-councils-call-for-evidence Now he has lots of free time(!) having stepped down from running the Royal Society, Sir Paul remains the biggest name in scientific establishment, or at least the first name in the section marked ‘scientists’ in David Willett’s former […]
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Editorial: Developing peer review

Posted by on April 7th, 2015

This editorial first appeared in Development.   Those of you reviewing for Development from this week onwards will notice some changes to our Reviewer Guidelines and Report Forms. After consultation with our Academic Editors, Advisory Board and the wider community, we have significantly revised the form that referees complete when reviewing a paper. We hope that these modifications will help our […]
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Best method to measure force transmission between cells

Posted by on April 6th, 2015

We have been trying to implement FRET in the lab and transfect our cells with mechanical biosensors, but so far we haven’t managed to successfully force our cells to express our constructs. After some digging, we realised that this technique does not work for all cell types. Its success seems to be highly dependent on cell […]
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Mole’s Wow! So now you have your own lab! Part II- The teaching monster

Posted by on March 31st, 2015

This cartoon was first published in the Journal of Cell Science. Read other articles and cartoons of Mole & Friends here.   To read part I- ‘The imposter’ click here.
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Mole’s Wow! So now you have your own lab! Part I- The imposter

Posted by on March 31st, 2015

This cartoon was first published in the Journal of Cell Science. Read other articles and cartoons of Mole & Friends here.     To read part II- ‘The teaching monster’ click here.
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