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The Node is a place to share news about and with the developmental biology community around the world. If this is your first time on the site, check out this introduction to the Node. You can also find out more about us, and sign up to contribute.
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Catching up? Read the monthly highlights on the Node.
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This month on the Node- February 2015
Posted by the Node on March 2nd, 2015
Our jobs page was again very busy this month, so make sure to check it out! Here are some of the other highlights: Research: - Manuel wrote about his Development paper, where he examines how the eyes of the cavefish P. andruzii develop, and what that tells us about the evolution of eye loss in […]
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This month on the Node- January 2015
Posted by the Node on February 2nd, 2015
Our jobs page has been busy this month, with several new postdoc positions advertised. Here are some of the other highlights: Research: - Christoph and his colleagues wrote about their recent Development paper, where they inhibited the Rho-kinase ROCK in the rabbit embryo, discussing the implications of their work in our understanding of the evolution […]
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Top Node posts of 2014
Posted by the Node on January 5th, 2015
Happy new year everyone! The last year saw the usual varied mix of news, research, meeting and discussion posts. We had a look at our stats to find the most popular posts of 2014: Most viewed posts: 1- The secret to getting the postdoc you want- former SDB president Martin Chalfie shares his thoughts on […]
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This month on the Node- November 2014
Posted by the Node on December 1st, 2014
Our jobs page was busy this month, with jobs advertised in the UK, France, Brazil, Finland and the USA! Here are the other highlights: Research: - Patrick told us the back story to his recent Nature paper that reported a common evolutionary origin for the external genitalia of a snake and the hindlimb of a […]
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This month on the Node- October 2014
Posted by the Node on November 3rd, 2014
Here are some of the highlights for October. Don’t forget to also check our jobs page, were several new positions were advertised this month! Research: - Shusei wrote about his recent paper successfully using intracytoplasmic sperm injection to generate live quails, and what this work teaches us about bird development. - Misato combined atomic force microscopy […]
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This month on the Node- September 2014
Posted by the Node on October 1st, 2014
Here are some of the highlights for September: Research: - Sylvain discussed his recent Development paper on the tristable regulatory network behind cell fate decisions in the early embryo. - Aryeh wrote about his research on spontaneous patterning of human ES cells, recently published in Nature Methods (he is also hiring a postdoc!). - and Christelle highlighted a recent […]
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This month on the Node- August 2014
Posted by the Node on September 1st, 2014
Here are last month’s highlights! Don’t forget to check our jobs page too. Research: - Gary wrote about his visit to a particle accelerator to image Xenopus embry0s using X-rays. - Thomas discussed his paper in Development on the evolution of the development underlying the complex cerebellum found in amniotes. - Milos introduced his blog ‘Creative Morphometrics’, where he […]
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This month on the Node- July 2014
Posted by the Node on August 1st, 2014
Here are last month’s highlights! Research and news: - Jacqueline wrote about her recent paper in Development, investigating the developmental origin and evolution of turtle shell patterning. - This month’s Stem Cell Beauty post focused on the role of two transcription factors in muscle development… and how the way such discoveries help us get closer to a […]
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This month on the Node- June 2014
Posted by the Node on July 1st, 2014
This month the Node celebrated its fourth birthday! Here are some of the other highlights: Research: - Kevin Chalut wrote about his recent paper at the crossroads of biology and physics, where he shows that the nucleus of ES cells exiting pluripotency have an unusual physical property. - How is the primitive […]
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This month on the Node- May 2014
Posted by the Node on June 1st, 2014
Our jobs page has been very busy again, including several positions in publishing. Here are some of the other highlights: Research: - Néstor discussed his recent paper in Developmental Cell on the role of GATA6 in primitive endoderm specification (and some of the techniques used). - Jenna and Jessica explained how they established zebrafish as a model to […]
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- pancRNAs in early development [IN THIS ISSUE]
- Uncovering neurogenic potential of striatal astrocytes [IN THIS ISSUE]
- Timing degradation to tune development [IN THIS ISSUE]
- Getting to the heart of heart cell identity [IN THIS ISSUE]
- Asymmetric division and fate in the retina [IN THIS ISSUE]
- Neural development and regeneration: it's all in your spinal cord [MEETING REVIEW]
- A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation [REVIEW]
- Auxin-induced degradation dynamics set the pace for lateral root development [RESEARCH REPORT]
- Gene activation-associated long noncoding RNAs function in mouse preimplantation development [RESEARCH ARTICLES]
- A MEIG1/PACRG complex in the manchette is essential for building the sperm flagella [RESEARCH ARTICLES]
- Contributions of Costal 2-Fused interactions to Hedgehog signaling in Drosophila [RESEARCH ARTICLES]
- Late Alk4/5/7 signaling is required for anterior skeletal patterning in sea urchin embryos [RESEARCH ARTICLES]
- Geometric control of ciliated band regulatory states in the sea urchin embryo [RESEARCH ARTICLES]
- The cytoplasmic domain of the gamete membrane fusion protein HAP2 targets the protein to the fusion site in Chlamydomonas and regulates the fusion reaction [RESEARCH ARTICLES]
- Wnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouse [RESEARCH ARTICLES]
- Muscle composition is regulated by a Lox-TGF{beta} feedback loop [RESEARCH ARTICLES]
- Drosophila small heat shock protein CryAB ensures structural integrity of developing muscles, and proper muscle and heart performance [RESEARCH ARTICLES]
- Extramacrochaetae functions in dorsal-ventral patterning of Drosophila imaginal discs [RESEARCH ARTICLES]
- Cell competition in mouse NIH3T3 embryonic fibroblasts is controlled by the activity of Tead family proteins and Myc [Articles of interest in other COB journals]
- miR-145 suppresses embryo-epithelial juxtacrine communication at implantation by modulating maternal IGF1R [Articles of interest in other COB journals]
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- Editorial Board
- Dpp/Gbb signaling is required for normal intestinal regeneration during infection
- Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development
- Diverse ETS transcription factors mediate FGF signaling in the Ciona anterior neural plate
- Insulin-independent role of adiponectin receptor signaling in Drosophila germline stem cell maintenance
- Loss of cftr function leads to pancreatic destruction in larval zebrafish
- Lizard tail regeneration: regulation of two distinct cartilage regions by Indian hedgehog
- Ontogeny of the mouse vocal fold epithelium
- RhoGAP68F controls transport of adhesion proteins in Rab4 endosomes to modulate epithelial morphogenesis of Drosophila leg discs
- Evidence for intermediate mesoderm and kidney progenitor cell specification by Pax2 and PTIP dependent mechanisms
- The heparan sulfate-modifying enzyme glucuronyl C5-epimerase HSE-5 controls Caenorhabditis elegans Q neuroblast polarization during migration
- Loss of function of the yellow-e gene causes dehydration-induced mortality of adult Tribolium castaneum
- Co-expression of the transcription factors CEH-14 and TTX-1 regulates AFD neuron-specific genes gcy-8 and gcy-18 in C. elegans
- The organizer in evolution–gastrulation and organizer gene expression highlight the importance of Brachyury during development of the coral, Acropora millepora
- Phospholipase C and D regulation of Src, calcium release and membrane fusion during Xenopus laevis development
- Claudin-10 is required for relay of left-right patterning cues from Hensen’s node to the lateral plate mesoderm
- More similar than you think: Frog metamorphosis as a Model of Human Perinatal Endocrinology
- Using Xenopus tissue cultures for the study of myasthenia Gravis pathogenesis
- Editorial Board
- Letter from the editor – issue 399/1–1 March 2015
- Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling
- Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland
- A dual epimorphic and compensatory mode of heart regeneration in zebrafish
- p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas
- Mice lacking the transcription factor SHOX2 display impaired cerebellar development and deficits in motor coordination
- Motor neuron cell bodies are actively positioned by Slit/Robo repulsion and Netrin/DCC attraction
- A diffusible signal derived from hematopoietic cells supports the survival and proliferation of regenerative cells during zebrafish fin fold regeneration
- Differential regenerative capacity of neonatal mouse hearts after cryoinjury
- Nephron proximal tubule patterning and corpuscles of Stannius formation are regulated by the sim1a transcription factor and retinoic acid in zebrafish
- Tie1 is required for lymphatic valve and collecting vessel development
- A requirement for Gch1 and tetrahydrobiopterin in embryonic development
- Sox4 regulates choroid fissure closure by limiting Hedgehog signaling during ocular morphogenesis
- The boule gene is essential for spermatogenesis of haploid insect male
- The requirement of histone modification by PRDM12 and Kdm4a for the development of pre-placodal ectoderm and neural crest in Xenopus
- The cochlear sensory epithelium derives from Wnt responsive cells in the dorsomedial otic cup
- A 190 base pair, TGF-β responsive tooth and fin enhancer is required for stickleback Bmp6 expression
- A genetic interactome of the let-7 microRNA in C. elegans
- Mesenchymal Wnt signaling promotes formation of sternum and thoracic body wall
- Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
- Cre recombinase-regulated Endothelin1 transgenic mouse lines: Novel tools for analysis of embryonic and adult disorders
- IFT46 plays an essential role in cilia development
- Integration of comprehensive 3D microCT and signaling analysis reveals differential regulatory mechanisms of craniofacial bone development
- BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints
- The myogenic repressor gene Holes in muscles is a direct transcriptional target of Twist and Tinman in the Drosophila embryonic mesoderm
- BMP-dependent gene repression cascade in Drosophila eggshell patterning
- Bark beetle controls epithelial morphogenesis by septate junction maturation in Drosophila
- An oncologist׳s friend: How Xenopus contributes to cancer research
- Editorial Board
- From classical to current: Analyzing peripheral nervous system and spinal cord lineage and fate
- Maternal-zygotic knockout reveals a critical role of Cdx2 in the morula to blastocyst transition
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- The yin and yang of kidney development and Wilms' tumors [Reviews]
- A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth [Research Communications]
- Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4 [Research Communications]
- The DREAM complex promotes gene body H2A.Z for target repression [Research Communications]
- Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt [Research Papers]
- A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation [Research Papers]
- Mechanism of siRNA production from repetitive DNA [Research Papers]
- The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses [Research Papers]
- Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation [Research Papers]
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- TSC1 Activates TGF-β-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition
- CENP-A K124 Ubiquitylation Is Required for CENP-A Deposition at the Centromere
- SCML2 Establishes the Male Germline Epigenome through Regulation of Histone H2A Ubiquitination
- Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry
- Mechanical Tension Drives Cell Membrane Fusion
- Nodal Signaling Range Is Regulated by Proprotein Convertase-Mediated Maturation
- Weaning Triggers a Maturation Step of Pancreatic β Cells
- A Dicer-miR-107 Interaction Regulates Biogenesis of Specific miRNAs Crucial for Neurogenesis
- Puzzling Out Neurodevelopment
- The Evolution of Early Neurogenesis
- Neuronal Aggregates: Formation, Clearance, and Spreading
- Genetic Changes Shaping the Human Brain
- Cellular Functions of the Amyloid Precursor Protein from Development to Dementia
- Programmed Cell Death in Neurodevelopment
- Microglia: Multitasking Specialists of the Brain
- Subcellular Patterning: Axonal Domains with Specialized Structure and Function
- Dynamics and Mechanisms of CNS Myelination
- It Takes a Village: Constructing the Neurogenic Niche
- Evolution of Patterning Systems and Circuit Elements for Locomotion
- Neuronal Regeneration from Ependymo-Radial Glial Cells: Cook, Little Pot, Cook!
