the community site for and by developmental biologists

Displaying posts in the category: Highlights [Clear Filter]

Sweetening with a pinch of salt: maximized Cas9 efficiency in zebrafish

Posted by on June 14th, 2016

  Alexa Burger, Mosimann lab, Institute of Molecular Life Sciences, University of Zürich, Switzerland. When I first heard about the “new” genome editing method in early 2013 called CRISPR-Cas9, I thought: “Never ever again will I work with targeted nucleases!” Now it’s mid-2016, we published our approaches to maximize Cas9 effectiveness in zebrafish with Development[…]

This month on the Node – May 2016

Posted by on June 1st, 2016

May was most notable for the departure of the Node’s brilliant Community Manager, Cat Vicente. Cat said her goodbyes here, but we’d like to take this opportunity to thank her again for her great work over the last 3 years. And Cat still found time to keep posting right up to the end – both[…]

This month on the Node- April 2016

Posted by on May 3rd, 2016

Here are some of the posts we featured on the Node in the last month!   Research – Chen-Hui wrote about skinbow,  a new system to study cell dynamics during epithelial regeneration in zebrafish. – Our latest evo devo post was by Andrew, who discusses his recent Development paper highlighting the similarities between Shh in the gill[…]

This month on the Node- March 2016

Posted by on April 1st, 2016

  Focus on organoids Following Development’s call for papers for their upcoming Special Issue on Organoids, we featured an interview with their guest editor Melissa Little, discussing her career and research on kidney development and organoids. Our question of the month focused specifically on brain organoids and the ethical issues involved. You can share your thoughts by leaving[…]

This month on the Node- February 2016

Posted by on March 1st, 2016

Research – Two different applications of optogenetics were highlighted on the Node this month. Giorgia wrote about how optogenetics can be used to control morphogenesis in Drosophila. Meanwhile, Clare and Rachel described how they adapted the phytochrome system to live zebrafish embryos, allowing proteins to be moved within a live embryo using light! – What is the relationship[…]

This month on the Node- January 2016

Posted by on February 1st, 2016

We’ve had a busy start to 2016 on the Node! Check out this round-up of new content, and remember to check our Jobs page for new opportunities, and our Events page to keep up to date with conference and course deadlines.   Research –What can zebra finches tell us about pluripotency? Raj posted about early[…]

Top Node posts of 2015

Posted by on January 4th, 2016

Happy New Year everyone! The past year presented us with the usual mix of quirky and interesting developmental biology, and we’ve had posts about new meetings, research, resources and more. Now it’s time to review the most popular posts of 2015!   Most viewed 2015 posts 1- The (developmental) biologists reading list– Cat asked about the books[…]

This month on the Node- November 2015

Posted by on December 1st, 2015

Our jobs page was very busy this month! Check out the 13 new positions available. Elsewhere on the Node:   Research: – Mike Levin explains how his group used artificial intelligence to produce a model that explains the all-or-none phenotypes seen in depolarised Xenopus tadpoles. – How do you express two genes stably and bicistronically[…]

This month on the Node- October 2015

Posted by on November 1st, 2015

Research: – Can we make embryos in silico? Miquel posted about his recent paper in Bioinformatics, and the modeling framework he implemented in the new tool EmbryoMaker. – What does YAP do? Muriel explained the role of this Hippo effector in the Xenopus retina. – Histones, regeneration and crickets were all present in Hideyo Ohuchi’s post. – How[…]

This month on the Node- September 2015

Posted by on October 1st, 2015

  Research: – Are cellular movements essential for the formation of Turing patterns? Two theoretical chemists posted about their recent paper in Nature Communications! – David wrote his recent paper in Disease Models & Mechanisms, where he developed two novel and complementary strains that facilitate genetic studies in the mouse.   Discussion: – Are PhD internships[…]