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February in preprints

Posted by on March 6th, 2017

Our latest monthly trawl for developmental biology (and other cool) preprints. See June’s introductory post for background, and let us know if we missed anything   Another month, another bumper crop of preprints covering everything from calcium waves in the fly to the first mutant ant line, plant superhero genes to rat embryonic stem cells. Plus,[…]

Seeing the world through fresh eyes

Posted by on February 20th, 2017

There are many different structures in our eyes that work in conjunction to allow us to see. These structures are strikingly similar between different species, from zebrafish to humans. The growth of ocular tissues must be tightly controlled in order to maintain the correct eye size and shape that allow us to see. This tight[…]

Gene editing stem cells with CRISPR could help understand brain tumours

Posted by on February 14th, 2017

This report written by Justine Alford and highlighting a recent Development paper originally appeared on the CRUK Science Blog.      Over the past 12 months, the acronym CRISPR has been popping up in science news left, right and centre. And for good reason. Hailed as a revolution in genetic engineering, this molecular toolbox lets[…]

New data reveals how gene knockouts affect whole embryo gene expression

Posted by on February 7th, 2017

New DMDD data released on Expression Atlas reveals the effect of single gene knockouts on the expression of all other genes in the mouse genome. The gene expression profiles of 11 knockout lines have been derived from whole embryos harvested at E9.5, and the results can be compared with wild-type controls using an interactive online[…]

This month on the Node and beyond

Posted by on February 7th, 2017

January was a productive month on the Node, with a variety of developmental biology content from the lab bench and beyond.   Research We heard from the authors of a bunch of recent papers, including Ripla Arora on her recent Development paper on imaging the implanting embryo and uterine environment in 3D, and Kyle Martin[…]

From our sister journals – December & January

Posted by on February 6th, 2017

Here we highlight some developmental biology related content from other journals published by The Company of Biologists. JCS kicked off 2017 with a Special Issue relevant to many developmental biologists: 3D cell biology. It’s packed full of commentaries, interviews, research articles and techniques, and well worth a browse.   Brian Stramer of King’s College, London, a big[…]

January in preprints

Posted by on February 3rd, 2017

Our latest monthly trawl for developmental biology (and other cool) preprints. See June’s introductory post for background, and let us know if we missed anything   2017 started where 2016 had left off, with an number of preprints covering most corners of developmental biology, plus more relevant work from related fields. Looking at the list below,[…]

In Development this week (Vol. 144, Issue 3)

Posted by on January 31st, 2017

Here are the highlights from the current issue of Development:   Evolving an atypical developmental programme with IMM The brown alga Ectocarpus has alternating haploid (gametophyte) and diploid (sporophyte) generations. Morphologically, these are distinguished by a more complex system of basal filaments in the sporophyte, initiated via symmetric divisions before the apical-basal axis is defined[…]

Lifemap: a zoomable interface for exploring the entire Tree of Life

Posted by on January 30th, 2017

“Nothing in biology makes sense except in the light of evolution” (Dobzansky, 1973). Our knowledge of the evolutionary relationships between all known organisms, the so-called Tree of Life (ToL), is crucial in all fields of biology. Many researchers in evolutionary biology are working on improving the quality and the comprehensiveness of this ToL. This implies[…]

Can you handle the tooth?

Posted by on January 23rd, 2017

Reflections on “Sox2+ progenitors in sharks link taste development with the evolution of regenerative teeth from denticles”, PNAS 113(51), 14769-14774, 2016.   Despite an overwhelming amount of carefully curated data, such as the International Shark Attack File, which indicates that your chances of being bitten by a shark are vanishingly small, humans have had a long and often[…]