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This year for Christmas, gift yourself with an amazing experience. Apply today for the 2018 CSHL Cell and Developmental Biology of Xenopus course.

Posted by on December 18th, 2017

The end of the year is quickly approaching, and if you are anything like me you are scrambling to try to get as much work done as possible before your holiday break. But while this frequently entails getting papers submitted, committee meetings completed, and experiments wrapped up, I also take the opportunity to reflect on[…]

November in preprints

Posted by on December 5th, 2017

Our latest monthly trawl for developmental biology (and other cool) preprints. Let us know if we missed anything.   This month in preprint news – here at The Company of Biologists, set just outside Cambridge in the UK, we’re hiring a new ‘Preprints Community Manager’. You can find out more here. It’s a great opportunity to get in[…]

Marie Curie PhD fellowship / Molecular profiling of cells during regeneration: cell diversity and evolution across phyla

Posted by on December 5th, 2017

A 3-year PhD fellowship in evolutionary developmental biology and genomics is available in the lab of Michalis Averof, at the Institut de Génomique Fonctionnelle de Lyon (IGFL) in France. The fellowship is funded by the Marie Curie ITN programme EvoCELL. Some animals have the ability to regenerate parts of their body (limbs, tail, internal organs)[…]

Looking back on the adventure: exploring cell fate conversion with single cell RNA-seq

Posted by on November 21st, 2017

The story behind our recent paper: Liu Z*, Wang L*, Welch JD*, Ma H, Zhou Y, Vaseghi HR, Yu S, Wall JB, Alimohamadi S, Zheng M, Yin CY, Shen WN, Prins JF, Liu JD, Qian L (2017). Single cell transcriptomics reconstructs lineage conversion from fibroblast to cardiomyocyte. Nature, 551, 100-104 *: co-first author. https://www.nature.com/articles/nature24454  […]

Synthetic Materials for Human Organoid Generation and Wound Healing (The Journey)

Posted by on November 20th, 2017

Looking back on the journey of: Ricardo Cruz-Acuña and Miguel Quirós et al. Nature Cell Biology (2017) The Start  On August 2013, I took my first one-way trip departing from Puerto Rico. Although I have always been passionate about travelling to as many places (the cheapest way) possible, embracing the PhD-journey in a new city[…]

October in preprints

Posted by on November 2nd, 2017

Our latest monthly trawl for developmental biology (and other cool) preprints. Let us know if we missed anything.   October was a monster month for preprinting (a burst of post-summer productivity?), notable for the number of preprints covering plant development, disease modelling, modelling modelling, neurodevelopment, and organisms ranging from polychaete worms to hemipterans, Arctic charr[…]

Worm study reveals role of stem cells in cancer

Posted by on October 3rd, 2017

A new study carried out by the University of Oxford has used flat worms to look at the role of migrating stem cells in cancer Researchers from the Aboobaker lab in the Department of Zoology used the worms (planarians) which are known for their ability to regenerate their tissues and organs repeatedly. This process is[…]

September in preprints

Posted by on October 3rd, 2017

Our latest monthly trawl for developmental biology (and other cool) preprints. See last year’s introductory post for background, and let us know if we missed anything.   This month features butterfly eyespots, brain development in vivo and in silico, lots on cell commitment in embryos and dishes, a diverse selection of modelling preprints, and, right at the end in our ‘Why[…]

Production of key diabetes cells can be improved

Posted by on September 22nd, 2017

In the future diabetics might benefit from getting insulin-regulating beta cells transplanted into their body because their own beta cells are destroyed or less functional. However, according to new stem cell research at the University of Copenhagen, the current way of producing beta cells from stem cells has significant shortfalls. The beta cells produced have[…]

2017 FASEB Mechanisms in Plant Development Meeting Summary

Posted by on September 5th, 2017

Written By: Margaret Frank, Ora Hazak, Samuel Leiboff, Heike Lindner, Concepcion Manzano, Lena Mueller, Michael Raissig, Annis Richardson, Adam Runions, Sebastian Soyk   A systems biology approach to understanding development The 2017 FASEB meeting “Mechanisms in Plant Development” launched with a keynote by Philip Benfey (Duke University, USA) about the current understanding of root development.[…]