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Journal club on the Node

Figure 1 Schematic of the clock model as proposed by Thorogood (1991). (A) The bold arrow represents the timing of the AER-to-AF transition in the developmental process. (B-D) Hypothesized representations of fin/limb development in the clock model (above) with endochondral skeletal patterns of the fin/limb (below,). (B) Fin development in a teleost, demonstrating a short period of time with AER signaling prior to the AER-to-AF transition.   (C) Fin development in lobe-finned fishes, showing a longer relative time with AER signaling prior to AF transformation. (D) Limb development in a tetrapod, in which AER signaling persists throughout limb development. Figure modified from Yano et al. [3]; based on Thorogood [2]; with fossil form representations in C-D from Long et al. [4].

If I could turn back time: an embryological look at the fin-to-limb transition

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Stem Cells in Developmental Biology: a debate at the BSDB

On how odd critters can answer important questions

Images from the International Course on Developmental Biology

Posted by on May 3rd, 2012

One of the covers of Development this year is reserved for an image from the International Course on Developmental Biology, UNAB, Quintay-Chile. This course ran from 5-17 January in Chile. You can read a report from the course on the Node.

Which image will get the coveted cover spot is up to you to decide. Choose your favourite before May 21st, noon GMT. There are 8 images to choose from. Click any of them to see a bigger version.

1. Six zebrafish



2. Drosophila ovaries, HisGFP



3. Planarian in situ



4. Planarian confocal



5. Sea urchin



6. Drosophila embryo, Knirps



7. Chick embryo



8. Xenopus embryo, sox3




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  1. Eric Edsinger-Gonzales says:
    More details for the images would help the decision process. What genes or proteins and/or what stages for instance. Other than a pretty picture, there is little substance to make a decision. But the pictures are all great!

    Eric


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    • Eva Amsen says:
      But the decision is based on which one would LOOK best on a journal cover, so it really is just about the prettiness at this point.

      Would the planarian confocal image, for example, look any better or worse depending on what is actually stained?


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  2. Bogdan says:
    I would also like to read more on how the pictures were made. Not to help me with making a decision, that’s already made, but for my personal curiosity.


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  3. rocio says:
    muy bonitas e increibles todas las fotos casi q parecen de ficcion


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