A 3-year DFG-funded PhD-position is available at the Jasper Collaboration Group at the FLI-Leibniz Institute on Aging. Our work focuses on the Drosophila intestine as a model for adult stem cell regulation and aging (http://www.leibniz-fli.de/research/associated-research-groups/jasper/).
In this DFG-funded project, we will focus on elucidating the mechanisms of entero-endocrine (EE) cell differentiation and the role of EE cells in age-related dysbiosis using a combination of genetics, transcriptomics and transcription-factor binding studies. Despite their importance in controlling animal metabolism, behaviour and immune responses, there is still a great deal to learn about how EE cells are formed from intestinal stem cells and the influence EE cells exert on the microbiome, organismal aging and stress responses.
We are looking for highly motivated individuals who are fascinated by stem cells, transcription factors and the genetics of aging. Experience with Drosophila, stem cell systems and/or bio-informatic analysis of NGS-sequencing data is a pre. Please contact Dr. Jerome Korzelius (firstname.lastname@example.org) about any details regarding this position.