Our research seeks to investigate the fundamental question of how cardiac cells sense and respond to their environment. Focusing on tissue interactions we seek to understand the mechanisms underlying the regulation of morphogenic and identity transformations that occur during development and disease. We use the assembly of the heart tube in zebrafish as our model with which to elucidate these mechanisms. Some of the specific research questions we are interested in include, but are not restricted to: how multiple tissues interact to regulate large movements? How intercellular adhesions are tuned during collective movements? How lumen formation is intrinsically and extrinsically encoded? and How the plasticity of cardiovascular identity is regulated? These challenging questions require we take an interdisciplinary approach, combining the genetic and imaging strengths of zebrafish with both biomechanics and systems-level methodologies.
Are these the type of difficult challenges that excite you? We are recruiting graduate students to join our laboratory. Contact Josh directly at email@example.com.
-More information about the laboratory can also be found at joshuabloomekatz.wordpress.com.
-Additional positions are available in our interdisciplinary graduate program in the department of Biology at the University of Mississippi. For more information about our graduate program including rotations please see biology.olemiss.edu