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Displaying posts with the tag: adhesion [Clear Filter]

Dating with cells – finding the right match

Posted by on August 23rd, 2018

It’s an age-old mystery of the heart: do opposites attract, or will like do better with like? We can now answer this pressing question, at least for Drosophila cardioblasts: cells prefer to ‘swipe right’ on a shared transcriptional profile, but the resulting relationships are stronger if there are some unattractive alternatives around to remind them[…]

The Curious Case of Protocadherin 19 Epilepsy

Posted by on March 12th, 2018

Daniel Pederick & Paul Thomas Comment on our paper: Pederick, et al. 2018. Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy. Neuron 97 (1).   Here we discuss the curious case of female-restricted epilepsy, an unusual disorder caused by mutations in the Protocadherin 19 (PCDH19) gene. How changes in this cell adhesion[…]